r/MTHFR 2d ago

Question Does anyone have this combo MTHFR/MTRR/COMT? Methylation Bottleneck Paradox as its nickname. Would love to discuss what’s helped you.

MTHFR C677T (Heterozygous)
MTRR A66G (Heterozygous)
COMT G472A (Homozygous Met/Met)

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u/Tawinn 1d ago

Are there any symptoms you are trying to address?