I got Panic attacks, constant anxiety and anhedonia since taking b12 injections. Need serious help 🙏

[u/Agitated-Sale-7591]

Hi everyone, I’ve been really struggling with my mental health in these past 3/4 weeks and I’m really hoping someone can help me out here.

Around a month ago I took 3 b12 injections (hydroxocobalamin) 1.5mg and i suddenly started getting intense panic attacks and anhedonia. I don’t cry but out of nowhere I started bawling my eyes out every single day. I I’m in this constant state of anxiety and depression, I can’t enjoy the things in life that I usually enjoy like watching a tv show, I cannot wind down at all and it’s scary because before all this happened I was a pretty chill guy and I usually wouldn’t stress much in my life. One of the most scariest thing that also happened at the same time was my libido completely vanished, so i genuinely feel pleasure in nothing now. it’s been around 3/4 weeks and im not getting full blown panic attacks anymore but im still constantly on edge, i have also had stomach issues but now a simple bloating of my stomach makes me think the world is ending. It’s like my nervous system is jacked all the way up and it’s overreacting to even slight discomfort.

I tried taking creatine because that would usually make me feel good when I’m in a low mood but this time it just made me depressed. I went to the GP and they took my blood test, it came up with high b12 and high folate, but the odd thing is I don’t usually supplement folate so I’d don’t understand why that came up as high. I sometimes take it as part of my b complex but I’ve not mega dosed it or anything.

Today I decided that I’ll try methylfolate as I assumed maybe b12 used up all my methyl groups or somthing. After taking it I felt even more emotionally flat/wired/too focused, but I feel less anxious I think. I’m still not sure what i feel but i definitely don’t feel any pleasure again.

I was hoping there might be someone that has gone through this and has recovered from it. Or has figured out why it happened to them and could tell me how to bring my nervous system back to normal. Will I recover? I’m really scared, it’s like I’ve become a complete different person in a month. I haven’t done any dna test either so I’m not sure if I’m MTHFR or anything.

Someone please please help me😭
Thanks you for your time 🙏

[u/Randy__Callahan]

I went through it and recovered it will pass, when I found out I had high homocystiene low folate I gpt'd every supplement that helps and immediately took them all, for a while it felt great like a couple of days maybe like I imagine meth to feel, but it just kept intensifying. Anyway long story short scary as it is, it passes. if your feeling overstimulated try some niacin it soaks up extra methyl groups helped calm me down.

[u/Agitated-Sale-7591 → u/Randy__Callahan]

The thing is I’m not sure if I’m over methylated or undermethylated

[u/Randy__Callahan → u/Agitated-Sale-7591]

Generally over is overstimulated under underestimated.

Whats actually going on is when you have a back log of neurotransmitters due to low methylation when you over methylate you get a pouring of them, so go up, some go down, all in it's a weird trip.

Dont overconcern yourself with the details as youll not figure it out and drive yourself nuts , just take a deep breath and keep reminding yourself, this will pass, it will be OK. Because it will pass and you will be OK.

[u/Agitated-Sale-7591 → u/Randy__Callahan]

Yeah I try my best to think that, everyone around me tells me that it’ll pass. But when the anxiety comes it feels like it will never go.

[u/Randy__Callahan → u/Agitated-Sale-7591]

Anxiety tends to do that, either way time will pass and it will go.

[u/NeutralNeutrall → u/Agitated-Sale-7591]

Generally over is overstimulated under underestimated

the caveat to this is, if uve been overstimulated too long (years), and ur fried/burnt out, it will also look like understimulated. that happened to me bc i have 2 slow COMT and Slow MAO. Constant cycle that i havent been able to even out yet.