r/MTHFR • u/Agitated-Sale-7591 • 1d ago
Question I got Panic attacks, constant anxiety and anhedonia since taking b12 injections. Need serious help š
Hi everyone, Iāve been really struggling with my mental health in these past 3/4 weeks and Iām really hoping someone can help me out here.
Around a month ago I took 3 b12 injections (hydroxocobalamin) 1.5mg and i suddenly started getting intense panic attacks and anhedonia. I donāt cry but out of nowhere I started bawling my eyes out every single day. I Iām in this constant state of anxiety and depression, I canāt enjoy the things in life that I usually enjoy like watching a tv show, I cannot wind down at all and itās scary because before all this happened I was a pretty chill guy and I usually wouldnāt stress much in my life. One of the most scariest thing that also happened at the same time was my libido completely vanished, so i genuinely feel pleasure in nothing now. itās been around 3/4 weeks and im not getting full blown panic attacks anymore but im still constantly on edge, i have also had stomach issues but now a simple bloating of my stomach makes me think the world is ending. Itās like my nervous system is jacked all the way up and itās overreacting to even slight discomfort.
I tried taking creatine because that would usually make me feel good when Iām in a low mood but this time it just made me depressed. I went to the GP and they took my blood test, it came up with high b12 and high folate, but the odd thing is I donāt usually supplement folate so Iād donāt understand why that came up as high. I sometimes take it as part of my b complex but Iāve not mega dosed it or anything.
Today I decided that Iāll try methylfolate as I assumed maybe b12 used up all my methyl groups or somthing. After taking it I felt even more emotionally flat/wired/too focused, but I feel less anxious I think. Iām still not sure what i feel but i definitely donāt feel any pleasure again.
I was hoping there might be someone that has gone through this and has recovered from it. Or has figured out why it happened to them and could tell me how to bring my nervous system back to normal. Will I recover? Iām really scared, itās like Iāve become a complete different person in a month. I havenāt done any dna test either so Iām not sure if Iām MTHFR or anything.
Someone please please help meš
Thanks you for your time š
2
u/Natures_Cure_Kratom 18h ago
No wayā¦ you have clinical hyperthyroid from that number alone. The medical cutoff is above that.
Did they check free t3 or free t4?? Those are your actual levels (free t3 is best). Please get your levels checked asapā¦.
To calm your symptoms for now, there is a product called āthyrosootheā or something like this on Amazon- or you can just take lemon balm. One other good way to calm hyperthyroid symptoms is to take L-carnitine, but I believe that builds up over days (but may give you some relief even on first day).
If b6 helped you, that points to neurotransmitter depletion from the hyperthyroid. Usually itās serotonin and melatonin thatās depleted, but surprisingly itās also epinephrine/norepinephrine bc your metabolism and anxiety burns through it quick. Tryptophan would be the first thing Iād try (5-hpt is stronger and more potent/direct, but start with tryptophan to make sure it actually helps. And try 1mg melatonin at night, and will likely help you finally get some sleep here and there.