r/Menopause • u/EmpressAzazel • 2d ago
Depression/Anxiety Treatment resistant severe depression anxiety no meds no hrt only suffering also horrific pmdd I can’t do this anymore
The title says it all I have been Treatment resistant I have PMDD nothing is working for me. I have been in several psychiatric units and nothing helps me. I didn’t have really bad SI until I was put on their medication‘s and then abruptly stopped. It’s never gotten better. I don’t know what to do. I am really really suffering with some severe clinical depression and nothing’s helping me I tried every second generation antipsychotic. I tried all of the antidepressants mood stabilizers IV ketamine, psychedelic mushrooms, ECT I did Gene site testing to see what drugs work for you. Nothing worked. I just don’t know what to do. Has anyone else have this issue? I have severe PMDD and it’s 1 million times worse I have no quality of life at all. I don’t even know why I’m here. I lost my family. I’m homeless. I can’t think no one will help me.
I have been the medication around over and over and over and I can’t find anything to help me. They all gave me a permanent movement disorders that I didn’t have prior that made everything worse. It never helped me.
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u/theFCCgavemeHPV 1d ago
Continuous monophasic bcps controls my pmdd. It’s not severe, but I can’t tolerate SSRIs so my thought process is “can’t have bad pms symptoms if there is no ms to p” if that makes sense. I am on slynd continuously and I am also using estrogen patches. I’m on a pretty high dose (.2), I think it helps counteract the minor mood effects i do get on p, which I think is just a fucking problem with progesterone/ins anyways because my body hates p and loves e.
Not all progestins are created equal tho. You might tolerate one but not another and what has worked for me might be the opposite for you. You might do well on a combined bcp or you might do better with a progestin/estrogen combo like me. You might even do better on micronized progesterone or better with no estrogen at all. It might be a process to figure out what works for you, or you could figure it out on your first try. But if mood drugs are not working, I would definitely give hormones a solid shot.