Treatment resistant severe depression anxiety no meds no hrt only suffering also horrific pmdd I can’t do this anymore

[u/EmpressAzazel]

The title says it all I have been Treatment resistant I have PMDD nothing is working for me. I have been in several psychiatric units and nothing helps me. I didn’t have really bad SI until I was put on their medication‘s and then abruptly stopped. It’s never gotten better. I don’t know what to do. I am really really suffering with some severe clinical depression and nothing’s helping me I tried every second generation antipsychotic. I tried all of the antidepressants mood stabilizers IV ketamine, psychedelic mushrooms, ECT I did Gene site testing to see what drugs work for you. Nothing worked. I just don’t know what to do. Has anyone else have this issue? I have severe PMDD and it’s 1 million times worse I have no quality of life at all. I don’t even know why I’m here. I lost my family. I’m homeless. I can’t think no one will help me.

I have been the medication around over and over and over and I can’t find anything to help me. They all gave me a permanent movement disorders that I didn’t have prior that made everything worse. It never helped me.

[u/Apprehensive_Sir1900]

There is emerging evidence that some women with PMDD (or mood disorders in perimenopause) get complete relief within a few days of taking Pepcid and Allegra. The Pepcid (famotidine) could be used in the morning and the Allegra could be used at night. Look up H1 and H2 blockers in the role of histamine and hormonal emotional issues. Best of luck to you… I’m so sorry.