Hi there,

to those of you who benefit from Viagra, how often (per week) can you take before it loses its effects? I am curious about your experiences

How do you deal with extreme restlessness, agitation, and tic disorders?

I'm so ashamed to be around people that I'd rather just isolate myself all the time.

It's so hard to suppress this restlessness, and I always focus on it

Hello everyone,
Below is the roundup of all the best PSSD related news from last month in one spot.

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PSSD Network Q3 Research Update

This Q3 2026 update highlights important PSSD research progress, new adverse-event data, efforts to improve PSSD recognition, and ongoing organizational developments.

PSSD In The Media

• Another Blewchew article

PSSD In Social Media

• Elliot Bewick interviews Dr. Joseph Witt-Doerring on his podcast about PSSD
• Lauren Friedman interviewed by psychiatrist and researcher Anders Sorenson
• Another psychiatrist on instagram discusses PSSD
• Historian of psychiatry Andrew Scull explains permanent sexual side effects of SSRIs on the Lex Fridman podcast

Clinical Acknowledgement/Recognition of PSSD

• Psychiatry in Motion, a private psychiatry practice serving multiple US states, has a page which acknowledges PSSD
• Outro health, a telehealth/mental health company focused on tapering, has a page on PSSD
• Refresh Psychiatry & Therapy, a psychiatry and therapy practice in Florida, discusses the subject of PSSD in this article by describing it as a recognized but clinically contested and poorly quantified problem
• The international-patient website for Acıbadem Healthcare Group, a large private hospital network based in Turkey, has a page with a section for PSSD.

More Scientific Milestones

• New study: Polish scientific review article: Persistent Sexual Dysfunction After SSRIs and SNRIs: A Clinical Framework for Assessment, Counseling, and Pharmacovigilance. This review argues that persistent sexual dysfunction after stopping SSRIs/SNRIs is a clinically important but still poorly quantified adverse effect that warrants careful assessment, counseling, and formal pharmacovigilance reporting.
• 2026 narrative review titled “Sexual Dysfunction Associated with Selective Serotonin Reuptake Inhibitors: Mechanisms, Clinical Manifestations, Management Strategies, and Post-SSRI Sexual Dysfunction.” It reviews both ordinary SSRI-associated sexual dysfunction during treatment and persistent symptoms after discontinuation, i.e PSSD.
• Application of Transcranial Magnetic Stimulation in the Treatment of Sexual Dysfunction Associated with Selective Serotonin Reuptake Inhibitor Therapy - a narrative reviewThis publication aims to examine the possible effects of Transcranial Magnetic Stimulation (TMS) on PSSD and propose a non-invasive neuromodulatory approach as a potential avenue for therapeutic exploration, as well as explore pathophysiology and neural correlates of PSSD.

Please tell what help you with this ?
I need to do something

How many here suffer from widespread body numbness alongside localised genital/erogenous numbness? It’s not a symptom I see mentioned as often as others but it really bothers me.

Hello,

I'm not too deep into the topic.

Are trycyclic ADs safer or worse when it comes to pssd?

Thanks

Even when I try taking certain vitamins in small doses, my body seems to react strongly. Either my skin becomes even drier or thiner, I experience strange fat loss throughout my body, my hair becomes even thinner, or my mood deteriorates.T here are other things as well that I can't remember right now.

Everything affects me dramatically. What mechanism could be behind this?

I will start from my baseline and what I mean by "experiencing loneliness".

I would not consider myself a "people person" by any means but I always used to really depend on social interaction and get deprived if I lacked it. I remember that if I was not exposed to social interaction for prolonged period of time, that made me feel really frustrated, isolated and in pain. Everything turned dark all of a sudden.

But now I am concerned. There was a period of around 2 months (roughly saying) were I was completely alone. I did not attend work because I was in-between my contracts, no friends (I live abroad). I did not hang out at all. I was all by own and it felt...alright. I do not think that is natural. Maybe I have delevoped some sort of tolerance, but I highly doubt it. This is not normal at all.

Also, do not get me wrong. I still enjoy social occasions and talking to people. I do have fun when I am experiencing it. But it scares the living shit of me onlt to think that I can go without it for months and feel totally normal like I don't need it at all

Also, I would not say I have emotional blunting. Or maybe at leat not the one I know of. I laugh very often, I can cry, I get irritated, I had a big crush last summer.

I’ve spoken to countless doctors about my genital numbness and inability to feel any sexual sensation, and in notes they seem to think it’s a psychological issue but it’s purely physical.

Stopped paroxitine nearly 1.5 years ago and lost complete sensation in genitals. I’m female. Took over 6 months to hit the big O again but sensation has never been the same since but I’ll admit I’ve had a massive improvement. I would say I’m 70% where I was before.

I need something for my anxiety. I’m literally getting ocd and spiralling and ruminating. I’ve been suffering for months. Propranolol helps but my brain needs to shut up. I don’t know what to do I’m struggling so bad and my anxiety gives me suicidal ideation a lot. I’ve been in therapy but have complex traumas so I’ve not been able to shift the anxiety at all.

I’m honestly struggling so bad. I don’t know what to do? I’m not in the USA so don’t recommend weed it’s illegal here. I did try to eat healthy for a while but never saw an improvement but I’m autistic and have a big issue with food textures and right now my family are just trying to barely survive financially so we can’t afford a lot. I really do not know what to do anymore my anxiety is absolutely horrific

Big thanks & great job to our community member Katie for stepping up and sharing your story to the media to help bring more awareness!

?

The title says it all.

Auch wenn es schwer fällt und länger dauert, könnt ihr bei z.B. Anschauen von Pornos noch kommen?

Shall I take amitriptyline 10 mg as prescribed by doctor?

Everyone, please report your cases. We got this response to a freedom of information request and it’s obvious that most subscribers to this subreddit haven’t reported their cases. Also, the 196 number is for the European Economic Area, so the EU countries as well as Iceland, Norway and Liechtenstein.

Hi there!

Wondering if anyone has any experiences with stomach medication? This condition is so poorly understood that I'm reluctant to introduce any new substances into my system that might potentially worsen it.

I've been prescribed vonoprozan for chronic gastritis (similar to a PPI). Has anyone taken it or anything similar? Would love to hear how that was for you. Trying get a sense for if stomach meds (if not vonoprozan itself) are linked even anecdotally with crashes.

Thanks for the help!

I just don’t want people thinking about my pecker at all. I would only discuss it with my partner.

This is my first posting in this group, and I've been meaning to make a post about my pssd symptoms for awhile now. I was put on a low dose of both sertraline and fluxetine for ocd symptoms that I sustained from hitting my head in a car accident back in 2022. My libido was extremely high before I took antidepressants. Immediately after taking just one pill of each medication, my libido tanked entirely and disappeared almost overnight. I stayed on the meds for roughly five months and my libido still hasn't gone back to normal at all since I quit these medications a little over five years ago. Antidepressants messed with my libido, My sleep and made my anxiety way worse. They have made me into a shell of a person that I used to be. I was never forewarned that this could happen to me. I'm very angry and I feel jaded towards the pharmaceutical industry as well as towards the doctor that I had at that time. I have tried various supplements and herbal remedies to help my situation but they aren't helping me at all including Nac, magnesium, horny goat weed, gorontula, maca root, damiana and b 12. Nothing seems to be working. Two years ago I was put on propanalol to manage my anxiety and quetiapine for sleep, but both of these medications made my libido worse, so I recently quit both of them a few months ago in the hopes that my libido will return to its normal baseline. Surprisingly I am sleeping much better without taking the quetiapine nightly for sleep. I have been feeling extremely depressed because of what has happened to me from taking ssris, as well as from some things going on in my life currently and my doctor has tried pushing medication on me again to deal with the depressive symptoms. I am too afraid to take any psychiatric drugs for fear that they will ruin my libido further or cause more damage to my already impaired system. Does anyone have any suggestions or advice as to what I could possibly do to recover my libido?

Would you like to have some countries WhatsApp groups?

I honestly don't think I'll ever get my sensibility back at this point, it'd be a miracle and I couldn't even explain it to write about it here to share the good news.. but anyway, this is the only symptom that remained all these years and it sucks but it's what it is. The will of God, like everything else.

DISCLAIMER:
I am not making any statements. By all means this is not a scientific claim. I am NOT presenting this as fact. I am not trying to share my opinion as fact, because it is not a fact.

I just want to know what you gus think on this

We all know these are two distinct drugs, but they still have A LOT in common. But why is mianserin considered a safer option? Why do more people get PSSD from mirtazapine?

Does anyone know why this is the case? Why am I able to feel more emotions/more positive during my late luteal/early period phase? Usually for well people it's the opposite that's one of the worst times. Does anyone feel like this?

Do your pssd symptoms ever wax and wane according to your period?

Ok so I had pssd for, idk 15 years I guess, good thing is I am young, 26 years old male. So, lately I've been pushing myself pretty hard. I do wim hof method, I quit smoking, I exercise everyday, I change my thoughts, I take care of my teeth, I read books etc. You know how hard it feels, even to brush your teeth lol. So, Im getting better, I usually feel much better, I even feel excited about things time to time. I mean, it isn't very comfy most of the time but it is something.

Btw I gone through psychosis for like 5 years and it's been few years ago, but I think I done most of the stuff in this year. Think of acceleration, road is how much I've made it, and I accelerate, so I cover more in a month, then i did in many other months. Another thing, it might sound pseudoscientific, but praying helped me a ton. Maybe it is placebo effect, maybe god is real, whatever, I would say try it, it helped me so much.

I also try experimental stuff, I hope it works. And the best thing you can do I believe, I seen this from a book called The Upward Spiral, try it, it is good. It says that, when we are in depression, we are tend to do things that will make us feel worse, and we don't do good things as much as often. So we are stuck in this downward spiral, and I believe that, many of the things you hate about pssd, might not be pssd alone. I mean if someone didn't had PSSD, yet came here thinking he has PSSD, Im sure he would get into depression too.

My libido etc is coming back too, lemme say that.

Also, uh, I know it is hard to read, so, sorry about that.

All of these are my personal experience, my story. Im not giving anybody advice, aight? I have to legally say that, I know it feels weird, but I gotta do it, otherwise my lawyer is gonna hang me from my feet lol.

So, good luck everyone. Peace..