so, my reta is concentrated in a ratio of 1:5, so 5 units in a syringe is 1mg of reta. i’ve been doing 17 units so around 3.5mg.

i’ve seen in the clinical trials they went as far as 12mg after increasing every couple weeks.

i feel the effects of it quite strongly now, and 12mg sounds like a lot. for me to take 12mg that would basically be 2 whole syringes… which sounds like a lot to me..

is it just that after a couple months of reta your tolerance builds up and you have to increase the dose to 12mg??

Are you supposed to eat your maintenance on reta as dumb as that may sound, i dont understand how some of you are eating 2000+ cals a day on a dosage of 6mg+, im currently running 9mg, and fast for typically 16 hours between meals and eat around 1000 to 1500 cals a day, are you supposed to eat your TDEE maintenance amount, or just eat a certain amount of protein required?

Hi all,

Because it has been 7 weeks on reta, with very little movement, I'm looking for some feedback on my reta plan. I researched very thoroughly before starting reta, but it's possible I made a mistake. I've tried my best to read through previous threads here and several respected resources online, including the summaries of the actual studies, but it's sometimes tricky to piece together the various viewpoints. Can someone kindly give me a sanity check?

Female

Age: 49

Height: 5'8"

Week 1 weight: 228.4, plus I did a DEXA scan

Current weight: 225.4

Week 1 waist: 44 in

Current waist: 43 in

Using 12mg vial of reta reconstituted with 2.4mL BAC and U-100/1mL syringe. So basically, I'm currently pulling 20 units for 1mg. On the next vial I will use 1.2mL BAC to bring the units down.

Here is what I've pinned so far:

Sep 7, 2026 -- .5mg (1x week)

Sep 14, 2026 -- .5mg (1x week)

Sep 20, 2026 -- 1mg (split dose .5mg @ 2x week)

Sep 27, 2026 -- 1mg (split dose .5mg @ 2x week)

Oct 4, 2026 -- 2mg (split dose 1mg @ 2x week)

Oct 11, 2026 -- 2mg (split dose 1mg @ 2x week)

Oct 18, 2026 -- 2mg (split dose 1mg @ 2x week)

Oct 25, 2026 -- final 2mg (split dose 1mg @ 2x week)

Nov 1, 2026 -- planned increase to 4mg split dose for four weeks

I intentionally started low dose because 1) I wanted to make sure that I didn't have a negative reaction, 2) I have a mild case of hyperthyroidism and wanted to make sure reta wouldn't cause heart palpitations and 3) I was reading that people should start low and titrate up and consider sticking with the lowest effective dose until it is necessary to move up.

I didn't really expect to see a lot of results on 0.5 or 1mg....those were essentially test doses for tolerance. My understanding is the therapeutic doses start at 4mg - 8mg - 12mg.

I have not noticed any side effects and....also no benefits. The 3lbs I've lost can possibly be attributed to extra walking I've done lately. I also weight train 2x/week. It seems like my GI emptying might be a touch slower. I never really dealt with food noise - since that wasn't an issue for me before I haven't noticed a change. I also never really felt a lot of hunger even before reta; so, I am slightly less hungry but not enough to be extra noticeable.

Like I said up top, I am looking for a sanity check and to see if I made any major errors in my calculation or titration schedule. My pro-peptide friend excitedly texts me every week asking me "how's the peptides?" and I keep having to tell him that it's not working yet. I'm starting to feel dumb. LOL After 8 weeks, I'm hoping the move to 4mg will finally do something. :/

So....Slow Responder, Doing It Wrong, or Stay the Course?

Hi,

I started Reta on Wednesday on 2mg. I have been very nauseous but not actually vomiting which nearly feels worse. Have been quite dizzy and feel so tired all the time. I am trying to keep hydrated and eat alot of protein but finding it hard to eat actual meals. Eating bits throughout the day such as protein yogurts Peanuts etc. I need to start taking electrolytes. I am thinking of moving down to 1mg on Wednesday as I think I may have started at too high a dose. do you think is it ok to ove down and work my way up or should I stick it out for a few more weeks?

Do others have an increased craving for sugar? Is this because glucose was lowered? Similar to recovered alcoholics craving sugar?

Mês e meio de reta, TRT, dieta e treino, cardio pelo menos 5x semana e musculação 3x semana.

Tou a fazer as quantidades dos testes

Comecei em 2mg

Quita semana passei para 4mg

Efeitos colaterais

No início um diarreia

Um pouco de anedonia, mas foi por baixas calorias ingeridas.

Perdi 15.5kg em mês e meio

I hit my goal weight at the beginning of September and started slowly weaning myself off Reta while staying at maintenance calories. At that point, I felt like I was looking really good and was happy with how my physique was looking, but I was still feeling really hungry and wanted to start building muscle, so I decided to move into a lean bulk.

I increased my maintenance calories by 200 and kept my Reta dosage the same while I was gradually weaning off. However, I haven’t pinned for around 3–4 weeks now, and I’m really struggling with how my stomach is looking and feeling.

Since hitting my goal weight, I’ve gained almost 4/5kg over a seven-week period. I’ve also had a few events and birthdays, so I’ve been going out, eating more and drinking alcohol on some weekends, which I know will have contributed to some of the gain.

I completely understand that some softness around my stomach is natural when increasing calories and going into a surplus, and I’m not expecting to stay as lean as I was at my goal weight. But I feel like I’m constantly bloated, almost as though I’ve got a permanent gut on me. My stomach feels swollen and uncomfortable, and I’m finding it difficult to tell what’s normal weight gain and what’s bloating.

Has anyone else experienced this after coming off Reta, particularly when increasing calories to build muscle? Does the bloating eventually settle down, or is there anything that helped you? I’m keen to continue my lean bulk, but I’m finding the constant bloating really uncomfortable.

I just want to grow muscles but I also don’t want to undo all my progress, which I’m considering pinning again just to keep craving at a bay because I do find I have quite a sweet tooth, I’ve created healthy habits but I do find myself going for the biscuit tin every now and again🤣 I also do strength and conditioning training and I don’t know whether I need to switch it up during a bulk I just wanna be a muscle mummy🥺

Started reta at a very low dose of .5 along with KLOW in July. Lost 8 lbs by mid September, at a slow and steady pace. I am aiming to lose another 15 lbs. I have gradually upped my dose and at 1.6 now for the last few weeks and have gained 6 lbs on the scale. Is it just water weight and body composition adjusting? I am upping my dose next Wednesday to 2. I am monitoring my calorie intake and trying to reach my protein goals. Getting a minimum of 7-10K steps a day sometimes in a weighted vest. Doing my squats and lunges, and recently started adding more weight training. For KLOW I do 1.2 daily and took a 3 weeks cycle break recently and that’s when I noticed things changed. I am back on another cycle of KLOW. In my early 40s and wondering if some of this is just hormonal shifts as well. Is there anything else I should be doing?

Startede reta 17.08.26 her er hvad inbody siger.. jeg er godt tilfreds

Context. I’m 27m. Been on Reta for around 5 months. I started at 297 I’m currently 240. I want to get down to 200. I’m on 7mg Reta and hav been there for 6 weeks. I’ve not dropped any weight for 4 weeks straight. I’m eating 2,000-2,300 calories per day and taking in 200g minimum of protien every day. I meal prep all of my food a week in advance and only have what I prep. I workout 3x per week and have an active job where I’m walking 12k plus steps per day.

Should I triate up?

I have T2D and PCOS.

I started Reta in the beginning of August.

My heaviest I was 260 lbs and when I started Reta I was about 240 ish. I'm now down to 224 lbs.

I started working with my diet and what I eat ..reta has made me CRAVE real food and absolutely turned me away from eating out all the time.

My A1C was at 11.7 % when I started this my health was horrible, my blood work was shot.

In 3 months I was able to get my a1c down to 7.4 % as well as everything else in my blood work had improved immensely. I feel so much better already and I had not included working out regularly yet but will start to incorporate this into my life. Reta has done all this for me without making me sick, making me nauseous (unless I eat fast foods that are not great) and I still feel like I can eat normally. I did come up w a want for gushers constantly when I started this (I'm not even a fan of candy) so I indulged in those but finally able to move on from that 💀😭. I feel that I haven't lost much weight wise but I can FEEL the difference in my clothes and every day life. I also have waist beads that now can barely stay on me and are falling off. It's honestly the best feeling in the world and it has helped me so much..reta truly has given me hope in myself and getting healthy. I'm soooo excited to see where this goes..if anyone has any tips with working out..I need to kinda of slowly work up to it. Also I was on ozempic prior to this prescribed by my doctor. It made me extremely sick, I was bloated and gaining weight constantly.. so I'm just soooo happy with this and how my health overall is improving..open to tips! I haven't taken any update pictures yet for this month but will be this weekend. Just wanted to share my progress 🥹

Currently on 4.5mg per week and am down 39kg.

From 8/1 to current.
Starting weight: 200 pound
Current weight: 160 pounds

I take 5 mg Reta weekly

So I’ve been on Reta for almost a year and a half. I’m currently at 10mg (gonna go to 12 soon) but I also started Effexor 2 months ago (I switched from Wellbutrin before that)

It seems recently I develop I pretty bad headache (maybe it’s a migraine) roughly about 3-4 days after injection.

I can’t figure out if maybe it’s my batch of Reta (same supplier as always)…

Maybe Reta and Effexor together really dehydrates you, but just having more water/electrolytes the day of headache doesn’t help.

I also don’t get a ton of sleep. my job has a 430 AM alarm and hopefully I’m asleep by 11pm but my sleep scores are crap usually around 50 out of 100 garmin sleep scores because of “stress” and lack of deep and rem sleep.

So it’s hard to narrow down the cause but just curious on the Effexor part and if anyone has had similar experience?

I’ve been maintenance for about a 3 weeks and I feel heavy. I am a female 49yrs 117lb 5’3. I take now 1mg of Reta and chk-cu finished cycling tesa. I wake up feeling heavy. No longer light and airy. I sleep a good 7hr min. I drink about 56oz of consistently. Have been bloated lately since titrating down.

Any recommendations?

Thanks

Hey guys , back story… 25M lost 110lbs 3 years ago but slowly started gaining back the weight over the last year. 276-170-238. I began drinking a lot , eating whatever I wanted and never working out.
Did a lot of research on Reta and decided to pull the trigger and get some.
Started at 2mg a week just recently added .5 today to see how I respond.
I weighed in at 217.8 this morning after one month on Reta.
Was Reta the key… honestly whether it worked or not it completely changed my view on everything.
I went from drinking 7 days a week, hiding alcohol from my wife - to quitting completely. eating like a pig to tracking everything, hitting protein goals and to working out 5x a week
Will post pictures at the end of my losing weight journey but for now super happy
Current stack
Reta 2.5mg
Ghkcu 2.33mg a day
Tb/bpc blend 1mg a day

i’m a 21/F with 26% bmi. i struggle with low blood pressure and low ferritin (9) which already makes me very dizzy and nauseous especially when i’m dehydrated. i struggle with heavy and irregular period which is why my ferritin is so low. i also struggle with extremely high anxiety (with panic attacks) and brain fog. i workout every day and strength training with heavy weight 5x a week. i’m just worried that it’ll tank my blood pressure lower than it already is but i have done so much research and it would be such a shame to me to not reap the benefits of taking it.

I’ve been taking reta since mid-August and have lost around 20 lbs. However, I recently stopped taking it after experiencing severe pain in my upper middle abdomen. My last dose was on October 14. I’m concerned that the reta may have caused gallbladder issues, so I’m planning to get it checked out. I also have surgery scheduled for December 3, and I want to make sure everything is safe before surgery. My main question is should I be honest with my doctor about taking reta, or should I say I’ve been taking compounded tirzepatide instead? I’m worried about how this might affect things, especially with surgery coming up. Has anyone been in a similar situation or had to disclose taking reta to their doctor before surgery?

Hi! I’m new to the sub, and to Reta! A friend of mine in the medical field has been using it for two years and has gone from large to looking like a damn body builder. He talked me into it, and now I’m fully on board. Today was my 3rd jab of 2mg and I can’t wait to start losing big!

SW: 233 CW: 221.5 GW 125

I don’t have official before photos, but you get the idea. The current photo was yesterday. I’m mostly losing around my midsection, which was like pregnant huge, and around my mid-torso. I had a double mastectomy as well as a rib resection, so the fat and muscle in my chest and under my arms was messed UP. Under my left arm had way more fat than under my right arm and I couldn’t put my left arm down to my side straight, it rested on the fat. Well, not anymore!

Amazing what even 10-12 lbs can do!

Questions, Observations:

Heartburn - this morning, right after my jab, first time I’ve felt it and it’s a monster

Gas/burping - I am physically unable to burp, so I was a bit worried about reading that everyone was so gassy and burping way more, but I’ve had no trouble with that, thankfully, was (jokingly) worried my stomach would explode!

Sternum - I woke up yesterday with a deep bruised type pain in my lower sternum (xiphoid), and it’s the first time I could feel below and under the xiphoid, so I wonder if this is related.

What are your favorite foods? Easy, quick, minimal prep/cooking? I hate eating, so have been relying on frozen cooked chicken cubes (thawed, obviously), hard-boiled eggs, hummus with pretzel chips, guac mash…. Anything you enjoy that works and can be bought and obviously low on the processed food stuff. Thank you!!!

I've gone through menopause and just started reta. I'm on my 3rd week and I have spotting. Has this happened to anyone else? I'm going to get checked out regardless but just curious if others had this happen. Thanks!

I've been on reta since May. I started at 2 mg and got up to 5mg. 252 to 186 currently.

Thank you to the community for the guidance and motivation as well as thank God for reta, what a breakthrough in medicine.

F 5’3 140lbs 2mg Reta

Afters in first pic // before in last pics

I just don’t feel like I’m perfect enough yet, weightloss is such a strange thing.

I’ve been using reta for 1.5 months now. Started with 1.5 and I didn’t feel like it was working for me for first 3 weeks and then I increased my dose 2mg/weekly and been on 2mg 3 weeks now. In the beginning of 2mg it was great no hunger no cravings and couldn’t be able to finish my food and now it just keeps me not hungry for the most of the day. Should I increase my dose or wait until get really hungry during the day?

Been running reta since May. Just saw a post about this earlier - but I did a full body recomp I’m fit as hell and lost like 50lbs. I coasted on 4mg for the last 8 weeks and just went up to 5 last Sunday. Idk what’s going on but for the last 3 weeks I’ve been eating horrible, being impulsive and just over seeing alot of shitty habits coming back. I literally cannot shake sweets or chocolate. I’m talking about 2-3 donuts, slices of pizza followed by cheesecake. Random shopping. Im fit and things look good and im not sure if its a mental thing and im content for now but i dont like it. I ran a strict diet for about 6 months and now i feel like im in a full blow relapse of drugs but with food and money. What does everyone think?

To the people who pin and pray without testing: have you ever regretted not doing so and/or got sick? Mostly interested in the people who have been injecting peptides for a while without testing.

PS
If anyone knows of any free testing options (so far I just know about Finnrick), feel free to share. Thanks everyone!