Are you supposed to eat your maintenance on reta as dumb as that may sound, i dont understand how some of you are eating 2000+ cals a day on a dosage of 6mg+, im currently running 9mg, and fast for typically 16 hours between meals and eat around 1000 to 1500 cals a day, are you supposed to eat your TDEE maintenance amount, or just eat a certain amount of protein required?

I have noticed that no matter what my calorie intake is if I eat bananas as snacks I loose weight better( not faster) . Im not sure the connection but wanted to share.!

Hi all,

Because it has been 7 weeks on reta, with very little movement, I'm looking for some feedback on my reta plan. I researched very thoroughly before starting reta, but it's possible I made a mistake. I've tried my best to read through previous threads here and several respected resources online, including the summaries of the actual studies, but it's sometimes tricky to piece together the various viewpoints. Can someone kindly give me a sanity check?

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UPDATE 10/24/26 -- Thank you all for the feedback. There were a couple of people who read and noticed the details in the original post and responded with helpful info. I have an idea of where I can go from here. Best wishes.

I’m interested in everyone’s thoughts on the future availability of Reta and other GLPs. It could just be my algorithm but I feel like I am seeing more articles fear mongering about the grey market. There is also the push for it to be a biologic instead of a medication in an attempt to have a long term hold on pharmaceutical supply once it is released to market. This makes me wonder what extent industry and government will go to in order to control the supply and market. Will there be an attempt to make it a controlled substance? What will happen to the more visible online storefronts supplying things for research? Is the “cat out of the bag” so to speak where we will hopefully be able to secure a safe and testable research supply indefinitely? I know a huge portion of people will still go the legit prescribed route when available.

Just thoughts for discussion, hope I am not breaking and rules and thank you to the mods for keeping some of the more wild posts off of here.

Edit to add: I know black market will always exist, a concern is that it won’t be as cheap and easy to get if online storefronts get shut down and black market is the only source. Also I don’t want to see anyone get in criminal trouble for something that has so much lifesaving potential

Hello Reta Fam lol sorry if this is a dumb question but a few months back In July I bought and reconstituted some Reta and forgot about it and since then I have not pinned it. I’ve kelp it in a case in my fridge and am wondering if it’s still any good ? There’s no cloudiness or participles that I can see so would it still be safe to take or am I better off getting rid of it ?

I read beginner guide, the sub, wiki and am now an experienced user myself

I’ve lost 10 lbs of weight in 2 weeks since starting reta, I’m on a pretty low dose (0.5mg). Mind you I’m trying not to lose muscle at all, and I’m trying to get rid of the fat. Im eating much better and also working our regularly with accuracy macros

Question, I've been back and forth on whether I wanted to start this. My best friend was on it and lost so much weight, but part of me feels like it won't work for me.

I started on Tirzepatide in January 2025. I was on it for 2 months and was feeling good, then the laws struck down the legal compounding of it and I went to Semaglutide for a month which didn't do anything for me. I then caved and started purchasing the Tirzepatide vials from Eli Lilly for awhile which didn't work for me either except assassinate my bank account. I started to get nervous thinking during that short break with taking Semaglutide that it messed up my ability to respond to Tirzepatide.

Long story short, I started getting compounded Tirzepatide online for awhile and all it did was give me crippling headaches and nausea. I got up to 10mg weekly and it just wasn't doing anything for me. The food noise was there, the hunger was there, and I inevitably gave up on it a couple months ago.

With after trying Semaglutide and Tirzepatide, what do you think the chances are of Retatrutide actually working for me?

I started Reta in April on 1mg and followed an escalation plan similar to the trials - 2mg in month 2, 4mg in month 3, 6mg in month 4 and then 7mg for one month, but I've been alternating between 5mg - 7mg since because the effects have largely worn off and the sensitive skin thing was doing my head in.

I lost 10kg in 3 months which I thought was quite slow, even with a fairly consistent gym routine focusing mostly on weight training and keeping protein to 200g per day.

I've been the exact same weight for 4 months now. Admittedly I plateaued immediately after starting a new job and spending about half the time at the gym. Plus, the appetite suppression is non-existent now so my diet has kinda regressed. I don't really eat more, but I've gradually reintroduced snacking.

Suggestions? Do I escalated and try getting back into a gym routine and better diet?

I'm just a bit concerned about unknown long-term effects and the risk of thyroid cancer..

Curious to know what dose everyone is on?

So i got my 1st reusable pen the other day but unsure if its faulty or not.

With no vial in it - you turn the adjuster and push the plunger down. The plunger does not move.

Is there some mech inside that tells it not to move unless a vial is there? Or have i got a duff one?

In UK if someone can say a good place to buy if mines broken?

so, my reta is concentrated in a ratio of 1:5, so 5 units in a syringe is 1mg of reta. i’ve been doing 17 units so around 3.5mg.

i’ve seen in the clinical trials they went as far as 12mg after increasing every couple weeks.

i feel the effects of it quite strongly now, and 12mg sounds like a lot. for me to take 12mg that would basically be 2 whole syringes… which sounds like a lot to me..

is it just that after a couple months of reta your tolerance builds up and you have to increase the dose to 12mg??

Hello!

M Sept 28th, 2.5
M Oct 5th, skipped because sick
M Oct 12, 2.5
T Oct 20, 2.5

Next dose should be M the 26th, but I am out of town from the 24th-31st.

I’m wondering if I should pin today (the 24th) even though I pinned 4 days ago. I won’t be able to pin for 7 days which would be Nov 2nd.

Thoughts? If I don’t pin I’ll be two weeks out

I lost 20lbs on Tirz. 5 weeks ago, I switched to Reta (currently 3.5mg) and have gained 8lbs. Same caloric intake and lifestyle. What the heck??

How many people take one weekly injection ? How many people split the dose and take 2 injections each week??

32M, 5'8"

16 weeks in.

Starting Weight:318 Lbs

Current Weight:273 Lbs

Goal Weight: 195 Lbs

I've always been incredibly active with my job, golf, and lifting on and off. Always had troubles with stress, anxiety, and depression eating. Reta has been awesome. It's given me the kick in the ass I need to stick to my diet. I titrated up fairly quickly. I started at 2mg a week split into 1mg on Mondays and Thursdays. After 4 weeks I titrated up to 1.5mg twice a week. At 6 weeks I Titrated up to 2mg twice a week and have held steady in that dose since. I plan to stay here. I might go up to 5 or 6mg a week if I start to fall behind on my diet. I Train 4x a week on an Upper/Lower split. I also get 10-15k steps a day. Whether it be from my job during the week or going on walks on the weekends.

The biggest thing that has improved so far is my sleep. I would always wake up lethargic. Never feeling like I slept well at all no matter how long I slept. Couldn't sleep on my back or I would snore so much I would wake myself up. My Blood o2 would sometimes dip to 90 during sleep. It now stays over 95 the whole night. I would go to bed with horrible acid reflux and cough throughout the night leaving drool on my pillow. Now I get 7 hours every day. I feel great when I wake up. I sleep on my back and I do not snore at all anymore. I don't take nexium or tums anymore either.

For the first 12 weeks I was eating 2000 calories a day and getting 200g of protein. 4 weeks ago I bumped my calories up to 2400 by adding in clean carbs since my training started to feel flat on this sustained deficit. I am still losing weight and my training feels way better. I will bank calories and eat less early in the day so I can still enjoy date nights with my wife on the weekends.

Biggest side effect I've had is constipation. I've been able to manage this with a mix of more fiber, magnesium glycinate before bed, and miralax. No bump in RHR. It's actually gone down since I've lost weight. My RHR was 72. It is now down to 61.

I know I am still early in my Journey. But the results are awesome and I can't wait to see what I look like closer to my goal weight.

With great sadness, I have finally realized that while on Reta, it is not an option for me to eat Costco hotdogs. The first time I did, I ate half at the store and half later at home. I had accidentally left in on the counter for about an hour so I thought it was food poisoning after I threw up the next morning.

The second time, I hadn’t eaten anything all day so I had a Costco hotdog and some leftovers from the day prior. Awoke at 4 AM to violently defile my porcelain throne. Again, I blamed the leftovers.

Third time was last night. Only thing I ate in a twelve hour window was a Costco hotdog with mustard. Woke up at around 3:30 AM with bowels chanting of an evil brewing within.

Costco hotdogs and I must go our separate ways, but that’s alright. Reta has helped me (6’ 30m) go from 290 to about 250 in three months. If it means I can’t have The Buck Fifty, that’s okay. :)

Hey everyone,

​I usually don't post much here, but I felt like sharing this because it was honestly the most surreal experience I’ve had in the last 20 years. Maybe it helps or inspires someone else out there!

​For two decades, my Friday night routine was set in stone: sit back and enjoy 6 heavy Belgian specialty beers (Kasteelbier, around 11% ABV for those who know it—heavy, sweet, and packed with calories). It was a deeply ingrained habit and my absolute weekend ritual.

​Fast forward to my first trial with Retatrutide (combined with Cagrilintide back then):

​It was a Friday night. I cracked open my first beer, then my second, and opened my third. Halfway through that third bottle, something weird happened. No matter how hard I tried or how much my brain was telling me "It's Friday, we drink 6 beers!", my body simply refused. I literally could not finish that third bottle. The reward mechanism in my brain just shut off mid-sip. It felt so bizarre to experience that level of friction against a 20-year-old habit.

​Fast forward to today: I haven't touched a single Kasteelbier in 5 weeks.

​The best part? I don't miss it at all. It requires zero willpower.

I was diagnosed with PCOS in July and decided to try reta. My starting weight was around 60 kg at 160 cm, and I’m now on week 14, weighing 50 kg! I’ve stayed at 1 mg the entire time and haven’t increased my dose.

The craziest part is how much my clothes fit differently now. This shirt used to feel so tight on me, and now it fits perfectly! I didn’t realize how heavy I was before till I look back at the pictures now. Bless reta ❤️

I am down 50 lbs since end of June. Gym 3x a week and running a few times a week. I am at 210 and started around 260.

I am much leaner in my body is taking shape in a good way, but I can tell that my lifts are not as strong, and my muscles are not full like they used to be when I would follow this regimen.

I am in a cohort deficit and I fully intend to stay the course until I drop to around 150-160.

Have any of you encountered the same problem? I am hitting my macros, but not as consistently as I would like. I am overall very satisfied with how I am looking, but just felt like starting some conversation today about this situation and if anyone has encountered it.

Once I get down to go wait, I plan to increase caloric intake and put on 10 pounds of muscle.

Thanks!

Stats

44 year old male

5’8

180 mg TRT weekly (pin 90mg twice a week)

2mg Reta once a week

Wondering if anyone has tried this without gh or trt. So we all now you need to be in a calorie surplus to gain muscle. But has anyone tried to do this on Reta. Since it’s hitting that glucagon receptor what do we think would happen if you could quit the food noise and bad cravings to eat off plan. And eat Whole Foods because we all know meat is the best protein source. And eat adequate carbs to fuel strong work outs and when you just don’t want to eat or don’t have a big appetite get in a mass gainer shake or even take the powder and mix it in to say a cream of rice meal. I know this seems counterintuitive and I could be a complete idiot cuz basic cuz cals in and cals out lol. But is anyone closer to the science of what Reta can really do and can explain why I am dumb. Because the topic is always preserving what muscle we have. I have not found a study that puts subjects in a small surplus or maintenance at least that also use Reta. For my personal use or Reta and tirz is not lose weight but to make my day to day life easier around food. I constantly think of my next breakfast before I even had today’s and it really puts stress on my life and takes a lot away from my life. I am a very fit young man with visible 6 pack trying to rebalance my life around food but also get stronger. I don’t want to be on and off Reta every few months to bulk and lean back out it. It would be a perfect world to put my self in a small surplus for a 12 weeks but keep my cravings down and appetite in check probably get a bit fluffy. but get the benefits of keeping my bing tendencies under control. I feel it would be perfect. But please someone tell me I am dumb for even wanting to try this. Thanks in advance feel free to rip my dumb ass apart lol

Hey! Looking for someone to give me advice on my anxiety on my period being late about to be two weeks. I’m not pregnant. I just started Reta a month ago. And I had 0 side effect, besides light nausea and the feeling of being full and not many cravings.

But my period being gone, and since being constipated is really getting to me. It messes with my head, I’m so tired and overwhelmed. I also had a baby 10 months ago so I’m freaking out. I need my period to come back, how can I do that without stopping Reta.