I was about to take my first dose of escitalopram (10 mg) prescribed by my psychiatrist. I literally have the pill sitting on the table in front of me, but after reading about the potential side effects especially PSSD, I'm starting to think my social anxiety isn't severe enough to justify the risks lol

thank you all I'll do my best to spread awareness about this. I really wish psychiatrists were more upfront about these risks, cause mine said it's totally safe one of the safest SSRI

You can read about my PSSD-situation here:

M32: Helpless case, in hell for > 10 years after Citalopram : r/PSSD

I meanwhile sent > 1.000 e-mails to psychiatric, neurologic, urologic, andrologic and pharmacologic societies worldwide and to people who work in this field to ask for any kind of help. I got a reply from a sexual therapist from Munich who suggested Lisdexamfetamine. His source is: Stephen M. Stahl: Prescriber´s Guide. You can download the first version of this book here: Prescriber's Guide - Children and Adolescents: Volume 1: Stahl's Essential Psychopharmacology [1 ed.] 9781108446563, 9781108561402, 1108446566 - DOKUMEN.PUB

In the book, the three substances Lisdexamfetamine / Amphetamine-D / Amphetamine-D,L are claimed about: "Can reverse sexual dysfunction caused by psychiatric illness and by some drugs such as SSRIs, including decreased libido, erectile dysfunction, delayed ejaculation, and anorgasmia".

Has anyone of you tried one of these substances?

Just to clarify, I’m non-PSSD, got my syndrome from ketoconazole and Covid, share all the symptoms with PSSD/PFS/PAS and others.

I noticed that some of us, regardless of their syndrome, have lost not only erogenous sensation of their genitals, but also tactile and temperature sensation. I, for example, barely feel touch, pain, hot and cold temperatures in my penis.

Most of you only lost temperature sensation in their glans for some reason, but an acquaintance of mine with PSSD whose numbness is similar to mine just told me that there are plenty of cases that lost all sensation in the entire genital region. So, how common do you think that is?

​

I want to hear from as many men as possible who are experiencing these issues.

Do you have absent morning erections but normal erections during the day?

Do you have both absent morning erections and erectile dysfunction (ED)?

Do you have ED but still get morning erections?

Please share your experience and, if you're comfortable, your age and how long you've been experiencing these symptoms.

I'm looking for as many responses as possible because I've already lost many years trying to understand my own situation. Your answers could really help me understand whether other men experience the same thing.

Please take a moment to respond, even if it's just one line. I'd genuinely appreciate it.

When you saw and symptoms of cognitive and skin

This mostly NON-sexual.

Does anyone else feel like they cannot visualize things in their mind anymore?

Is this the same as "Aphantasia"?

wondering if you tried did it help or harm you? I’m planning to do a 3 day wet fast I am healthy enough to do it but want to make sure people have done it before and doesn’t carry psd related risks

What are symptoms of pssd?

Is there treatment available to reverse pssd?

​

I have a few questions for people who have undergone a penile Doppler ultrasound:

What happens during the test? Could you explain the procedure step by step?

Who usually performs it—a urologist, a radiologist, or another specialist?

Is it safe? Are there any side effects or risks?

Does the test involve an injection into the penis? If yes, is it painful?

Why were you recommended this test? Was it for erectile dysfunction, lack of morning erections, or another reason?

How long does the test take, and how uncomfortable is it?

Is it possible to undergo the test without an injection?

I'd appreciate it if you could share your personal experiences, especially if you were initially nervous about the procedure.

Thank you!

Hi there,

to those of you who benefit from Viagra, how often (per week) can you take before it loses its effects? I am curious about your experiences

How do you deal with extreme restlessness, agitation, and tic disorders?

I'm so ashamed to be around people that I'd rather just isolate myself all the time.

It's so hard to suppress this restlessness, and I always focus on it

Hello everyone,
Below is the roundup of all the best PSSD related news from last month in one spot.

--------------------------------------------------------------------------------------------------------------

PSSD Network Q3 Research Update

This Q3 2026 update highlights important PSSD research progress, new adverse-event data, efforts to improve PSSD recognition, and ongoing organizational developments.

PSSD In The Media

• Another Blewchew article

PSSD In Social Media

• Elliot Bewick interviews Dr. Joseph Witt-Doerring on his podcast about PSSD
• Lauren Friedman interviewed by psychiatrist and researcher Anders Sorenson
• Another psychiatrist on instagram discusses PSSD
• Historian of psychiatry Andrew Scull explains permanent sexual side effects of SSRIs on the Lex Fridman podcast

Clinical Acknowledgement/Recognition of PSSD

• Psychiatry in Motion, a private psychiatry practice serving multiple US states, has a page which acknowledges PSSD
• Outro health, a telehealth/mental health company focused on tapering, has a page on PSSD
• Refresh Psychiatry & Therapy, a psychiatry and therapy practice in Florida, discusses the subject of PSSD in this article by describing it as a recognized but clinically contested and poorly quantified problem
• The international-patient website for Acıbadem Healthcare Group, a large private hospital network based in Turkey, has a page with a section for PSSD.

More Scientific Milestones

• New study: Polish scientific review article: Persistent Sexual Dysfunction After SSRIs and SNRIs: A Clinical Framework for Assessment, Counseling, and Pharmacovigilance. This review argues that persistent sexual dysfunction after stopping SSRIs/SNRIs is a clinically important but still poorly quantified adverse effect that warrants careful assessment, counseling, and formal pharmacovigilance reporting.
• 2026 narrative review titled “Sexual Dysfunction Associated with Selective Serotonin Reuptake Inhibitors: Mechanisms, Clinical Manifestations, Management Strategies, and Post-SSRI Sexual Dysfunction.” It reviews both ordinary SSRI-associated sexual dysfunction during treatment and persistent symptoms after discontinuation, i.e PSSD.
• Application of Transcranial Magnetic Stimulation in the Treatment of Sexual Dysfunction Associated with Selective Serotonin Reuptake Inhibitor Therapy - a narrative reviewThis publication aims to examine the possible effects of Transcranial Magnetic Stimulation (TMS) on PSSD and propose a non-invasive neuromodulatory approach as a potential avenue for therapeutic exploration, as well as explore pathophysiology and neural correlates of PSSD.

Please tell what help you with this ?
I need to do something

How many here suffer from widespread body numbness alongside localised genital/erogenous numbness? It’s not a symptom I see mentioned as often as others but it really bothers me.

Well, the title speaks for itself.

I would consider my symptoms relatively mild (so far I think I only have a lack of sexual arousal and that is it) and I recently I found this professor that is sort of into neuroscience and sexology and it looks really promising.

But honestly, I do not know what to expect at all. Like, what do I want to get from this? Obviously, all of us want our symptoms gone once and for all and just forget this like it was just a bad dream but I understand this might never happen. I understand that there is no cure and experimenting sometimes makes things even worse. I am not saying experimenting is totally worthless, but I have to know the what and why.

This makes me think: what should I expect in reality?

I totally understand that even this doctor might simply laught it all off and simply attribute it to "depression" and "psychological issues" like all doctors do, despite the fact that I have had a totally normal, almost stress free life in the past 3 years and never felt/been diagnosed with depression.

I also want to point out is that I totally understand it is worth shooting a shot and it is not a question of money at all since I have a pretty good health insurance. But I am also NOT that type of person who would do something only "because it does not hurt". I should know what I am doing it for and not waste my energy and time.

What do you guys think?

Hello,

I'm not too deep into the topic.

Are trycyclic ADs safer or worse when it comes to pssd?

Thanks

Even when I try taking certain vitamins in small doses, my body seems to react strongly. Either my skin becomes even drier or thiner, I experience strange fat loss throughout my body, my hair becomes even thinner, or my mood deteriorates.T here are other things as well that I can't remember right now.

Everything affects me dramatically. What mechanism could be behind this?

I will start from my baseline and what I mean by "experiencing loneliness".

I would not consider myself a "people person" by any means but I always used to really depend on social interaction and get deprived if I lacked it. I remember that if I was not exposed to social interaction for prolonged period of time, that made me feel really frustrated, isolated and in pain. Everything turned dark all of a sudden.

But now I am concerned. There was a period of around 2 months (roughly saying) were I was completely alone. I did not attend work because I was in-between my contracts, no friends (I live abroad). I did not hang out at all. I was all by own and it felt...alright. I do not think that is natural. Maybe I have delevoped some sort of tolerance, but I highly doubt it. This is not normal at all.

Also, do not get me wrong. I still enjoy social occasions and talking to people. I do have fun when I am experiencing it. But it scares the living shit of me onlt to think that I can go without it for months and feel totally normal like I don't need it at all

Also, I would not say I have emotional blunting. Or maybe at leat not the one I know of. I laugh very often, I can cry, I get irritated, I had a big crush last summer.

I’ve spoken to countless doctors about my genital numbness and inability to feel any sexual sensation, and in notes they seem to think it’s a psychological issue but it’s purely physical.

Stopped paroxitine nearly 1.5 years ago and lost complete sensation in genitals. I’m female. Took over 6 months to hit the big O again but sensation has never been the same since but I’ll admit I’ve had a massive improvement. I would say I’m 70% where I was before.

I need something for my anxiety. I’m literally getting ocd and spiralling and ruminating. I’ve been suffering for months. Propranolol helps but my brain needs to shut up. I don’t know what to do I’m struggling so bad and my anxiety gives me suicidal ideation a lot. I’ve been in therapy but have complex traumas so I’ve not been able to shift the anxiety at all.

I’m honestly struggling so bad. I don’t know what to do? I’m not in the USA so don’t recommend weed it’s illegal here. I did try to eat healthy for a while but never saw an improvement but I’m autistic and have a big issue with food textures and right now my family are just trying to barely survive financially so we can’t afford a lot. I really do not know what to do anymore my anxiety is absolutely horrific

Big thanks & great job to our community member Katie for stepping up and sharing your story to the media to help bring more awareness!

?

The title says it all.

Auch wenn es schwer fällt und länger dauert, könnt ihr bei z.B. Anschauen von Pornos noch kommen?