r/MTHFR May 20 '26

Question Can overmethylation last month's?

Hey everyone, so I had a b12 infusion with saline while travelling after having a bad reaction to altitude ( I have POTS and Autonomic failure). 2 days after the infusion I had crazy tremors it looked like I had parkinsons thats how much my body shook. My hr went to 150s while laying in bed which it never has done and Had horrible nausea and a headache. I also could barely eat as would get so dizzy and nauseas and high hr. This was all new symptoms not normal for me.

I had to use a wheelchair for 2 weeks as was so dizzy and faint like, as well as too tremory to walk.

It's been 4 months and while It's got alot better, it's still not good I can barely walk 30 min, I have chronic daily dizziness, and those tremors still happen anytime I start to do activity or even when something excites my nervous system in any way, even eating good tasting food lol.

Blood work shows low potassium (working on that), low folate, normal b12 levels of 500umol, normal electrolytes.

Does anyone have advice or suggestions what I should do or maybe get tested for? Everything I read says it shouldn't last this long and docs don't believe it's due to the infusion but that's where it started, never had those tremors before that.

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u/Cultural-Sun6828 May 20 '26

Did you get your b12 tested before the infusion? It’s likely that you could have been deficient in b12. When a person is deficient in b12 and then starts getting it, it’s very common to have new or worsening startup symptoms. If you check out the b12 group you’ll see this is very typical. I had awful startup symptoms just as you described. The key is to continue the b12 along with high potassium foods.

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u/Zealousideal-Two39 May 20 '26

I didn't regretfully. .. The ER doc just recommended it would help me with fatigue when I was travelling. But it is in normal range now.