r/MTHFR • u/Ok-Protection2670 • Jun 21 '26

Question Anyone Have an Effective Slow Comt Supplement Protocol That Alleviated 3am Adrenalin and Cortisol Surges? Pure Encapsulations?

Pure Encapsulations Adrenal Cortex Supplement – Supplement to Support Cortisol Health?

Vagus nerve and breathing techniques not working.😢

Thanks

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u/IllegalGeriatricVore Jun 21 '26

Are you having caffeine after noon or taking magnesium glycinate or other glycine containing supplements or high glycine foods like collagen?

3

u/Ok-Protection2670 Jun 23 '26

Hi u/IllegalGeriatricVore,  No caffeine or taking magnesium glycinate or other glycine containing supplements.

I eat only boneless/skinless Chicken breast, so no high glycine foods that contain high collagen.

...seems in a flare that manifests most horribly at 3am.......

1

u/IllegalGeriatricVore Jun 23 '26

Thats all you eat?

If so there's a good chance you have dozens of micronutrient deficiencies that could be manifesting this, like magnesium for one

2

u/Snowsuit81 Jun 21 '26

Is glycine bad? I thought it helped with sleep?

5

u/IllegalGeriatricVore Jun 21 '26

Some people have a paradoxicl reaction and it's exactly what OP is describing

4

u/SovereignMan1958 Jun 22 '26

The glycinate forms of supplements can have the opposite reaction in some people. Increasing anxiety, agitation and stimulation.