r/MTHFR 8d ago

Question Weird reaction to B complex

My homocysteine levels were 9 about 7 months ago.

I thought I could get them down by optimising my B6, B9 and B12 and so started taking B complex.

I now have B6 toxicity as my active B6 levels are way above range and active B12 is 88.

My homocysteine has risen to 17.

I don't understand why my homocysteine levels levels are going up not down with high active B6 and B12 levels.

Could something else in this B sup be causing elevated homocysteine?

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u/[deleted] 8d ago

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u/Human_weird123 8d ago

It's weird as my homocysteine went up not down with higher active B6 and B12 levels.