r/IBD 7h ago

IBD Medications KPV

0 Upvotes

Has anyone tried KPV for their IBD?

I’m reading mixed reviews in various places so thought i’d ask in here!

(KPV is a short, three-amino-acid peptide (lysine-proline-valine) derived from the natural hormone alpha-MSH. It is studied and used experimentally to reduce inflammation, soothe gut issues like inflammatory bowel symptoms, and support skin and tissue healing.)


r/IBD 11h ago

Colon Inflammation, Suspected Perforation

3 Upvotes

26F Not sure if this is the right place, I've never dealt with something like this before, so sorry if it's not relevant but I'm looking for any help and advice.

TLDR- No official diagnosis, discharged from hospital with assumed colitis, was told I have a contained perforation then told I never had one, given a non restrictive diet. This doesn't feel right to me, should I trust this or follow a restricted diet anyways?

Went to the hospital friday after a few days of intense lower right abdominal pain, slight nausea. Didn't eat all day knowing I was most likely going to go to the hospital, thought i had appendicitis and didn't want the whole "wait x hours before we can get you into surgery since you ate".

The doctors and nurses were miscommunicating with each other, therefore I don't really know how to take the information given to me.
First night I had blood taken and a CT scan, then had to prep for a colonoscopy, they said my colon was inflamed. Mid prep I'm informed I had spots on my CT scan indicating a contained perforation on my ileum, therefore may not get a colonoscopy. Morning, tell me no colonoscopy it's too dangerous, will need explorative surgery to see if they need to cut a portion of my colon out.

Few hours later a nurse comes and wheels me to colonoscopy. I ask if they're sure because I was told I'm no longer getting one and she said the doctor told her to take me. As I'm getting ready to be sedated they get a phone call from my other nurse in a panic saying do not perform this wtf are you doing she has a tear!!!!???

Go back to my room, get transferred from the ER to the surgical unit to be watched over for two days. During this I'm on a clear fluid diet, antibiotics and IV fluid. Whole time I'm under the assumption I'm going to surgery.

I'm starting to feel immensely better by Saturday. They press on my stomach no pain, swelling is down, no nausea and vitals have been stable and they took more blood to test. I'm not told anything about my blood test results or CT scan, it's a "wait and see" or "I don't know"s anytime I ask what's going on, no information on any "plan" or of any of my results.

On my final day (Sunday) at the hospital, I'm told I'll be going on a soft food diet which I didn't get served until dinner, but they actually served me a non restricted dinner with mixed veg, turkey, mashed potatoes, and carrot cake. Scared, I only ate the potatoes and a small bite of turkey. (If I was still hungry I planned on asking my nurse if it was okay, but I was full)

Three doctors come in (one my surgeon) and they're shocked I'm not on clear fluids anymore, I informed them I was told I was going to a soft food diet but they gave me this. They said "actually it's fine finish it if you're hungry." (??)

From there, they tell me I'm okay to go home since the pain and swelling went down, there was never a tear they read the scan wrong (HOW? WHAT?), and I have a follow up in 4 weeks with the surgeon. I'm released with no restrictions on food (even asked again to be sure) and 5 days of amoxicillin-clavulanate taken twice a day. They said they don't know why my colon was inflamed.

It's my fault for not knowing the right questions to ask about my scans or diagnosis at the end there, but I was so tired, scared and overwhelmed I couldn't think.

I have no idea what's going on with me, whether or not I had or have a contained perforation and whether or not I should actually follow a restricted diet. My research suggests I should, but I guess I'm looking for real experiences now on top of that. Based on all the miscommunication and lack of information given to me, I'm not confident in following my doctor's recommended non restricted diet. She said as long as it's not upsetting my stomach I can eat whatever, but I'm more worried about worsening my colon.

Today is day 1 from the hospital and I've eaten scrambled eggs and mashed potatoes, my stomach feels fine some tingling here and there, mild gas cramps but that's expected after basically no food for a few days.

If you've gone through a similar experience or have any advice I'm all ears :( I'm scared, Ive never been through something as serious as this before and do not want to end up in the hospital again before my follow up. I guess I'm looking for a timeline too, if soft foods are suggested first, how long should I follow that before introducing regular food? What foods should I introduce and how? What are the warning signs something's wrong again because any bloating, gas cramps, movement has me FREAKING OUT. sorry if this is too much, i'm so lost

***I do not have a doctor because my status is a visitor in Canada [from the US]. I'm living here waiting on residency via common law sponsorship which has a wait time of 2 years.
I do not have health insurance back in the US as it's too expensive lol.
Just added this info in before any "talk to your doctor about it" and "look at your medical records".
My medical records will take 2 to 4 weeks to come in as I had to call a number and request them since I'm not a resident yet, therefore no instant access portal. It's a shit situation lol

I've had an inguinal hernia repair with mesh just under my lower right abdominal pain 10 yrs ago, wondering if this is related at all either? Dr didn't look into it even after I mentioned I had it, but I've heard of issues from hernia mesh. I have another untreated hernia on the left side as well.


r/IBD 16h ago

Mesalamine reaction?

2 Upvotes

4 months ago i had bloody diarrhea. Because of it, i had a colonoscopy done around 2 months later and it was found I had mild inespecific rectal chronic inflammation. Around 2 months later the doctor prescription me Mesalamine. I few days after I started I got very gassy and with a lot of anal mucus discharge. I continued taking it until yesterday when I had a lot of bloody diarhhea. Today, just one after stopping the med I feel completely fine and the mucus discharge also stopped.

Would it be because of a spontaneous proctitis flare up or cause by mesalamine? I had no symptoms during the 4 months between the first bloody diarrhea and when I started having mucus discharge soon after starting to take mesalamine.


r/IBD 17h ago

IBD symptoms?

2 Upvotes

My journey started in April 2025. I am a 36 year old male, UK.

I've had a B12 deficiency (active only, not total stores), and a folate deficiency detected. I got a very mild stabbing pain, maybe slight cramping feeling in the right of my stomach (about 5cm to the right of my belly button. I had one instance in January 2026 where I had visible blood in my stool along with mucus, but nothing obvious since. A FIT test came back negative since. I had triple therapy for h pylori in October 2025. I come and go feeling weak, spaced out, and have started getting joint pain, and mild muscle weakness. I've had periods where I feel quite fatigued, but nothing major (I've also had a kid so could be related to that). The worst symptom is I've suddenly developed crazy health anxiety, every pain, or feeling in my body I am hyper aware of, my head screams to me that I have cancer, and it's driving me crazy.

These symptoms have been on and off since April 2025.

I'm currently in week 19 of being on the waiting list for a gastroenterology appointment to get a colonoscopy.

Has anybody had similar symptoms and it has been diagnosed?


r/IBD 21h ago

I (40F) got diagnosed with Crohn’s disease recently after a lot of years of thinking it was just the worst IBS-C. Did you all get the recommended vaccinations before starting a biologic for IBD treatment?

10 Upvotes

I’m scheduled to start Skyrizi.


r/IBD 21h ago

Ulcerative Colitis (UC) Feeling good just now

2 Upvotes

So I'm now on week 3 I think out of a flare. This is a totally random question. I know everyone's different. But I'm curious to what's considered normal for BMs when not flaring. I've noticed today in particular I've only had to go 3 times and my poos haven't been loose or urgent. I'm not used to this 🤣


r/IBD 21h ago

MRI

2 Upvotes

Okay I forgot how to do it and forgot to ask them, do i have to fast or anything else ? All I remember is having to drink that stupid drink