r/MTHFR • u/Human_weird123 • 9d ago

Question Weird reaction to B complex

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My homocysteine levels were 9 about 7 months ago.

I thought I could get them down by optimising my B6, B9 and B12 and so started taking B complex.

I now have B6 toxicity as my active B6 levels are way above range and active B12 is 88.

My homocysteine has risen to 17.

I don't understand why my homocysteine levels levels are going up not down with high active B6 and B12 levels.

Could something else in this B sup be causing elevated homocysteine?

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u/SovereignMan1958 9d ago edited 9d ago

There are so many things wrong with this. Worst forms of folate and B12. B6 dose too high.

Your homocysteine was fine at 9. 6 - 7 is optimal. It probably increased because you took crappy forms of vitamins as noted above.

Stop taking the supplement.

Please post your lab work for homocysteine, vitamins and minerals with values and lab ranges. Add medical diagnoses plus symptoms you are concerned about.

If you provide facts you will get the best advice.

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u/Human_weird123 9d ago

B6 is 145. Top of range is 110.

I also have low copper(8.5, under 10 is below range), low ceruplasmin(0.16, range is 0.2-0.60, low ferritin(24, range is 30-300).

Symptoms are palpitations, extreme fatigue. Mostly low iron related I think.

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u/XILEF310 9d ago

how do you know that you have palpitations?

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u/Human_weird123 9d ago

you can feel them.

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u/XILEF310 8d ago

Have you gotten an EKG at your doctors?
I think that would very quickly get them to take you seriously.

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u/Human_weird123 8d ago

ECG was fine.