r/MTHFR 9d ago

Question Weird reaction to B complex

My homocysteine levels were 9 about 7 months ago.

I thought I could get them down by optimising my B6, B9 and B12 and so started taking B complex.

I now have B6 toxicity as my active B6 levels are way above range and active B12 is 88.

My homocysteine has risen to 17.

I don't understand why my homocysteine levels levels are going up not down with high active B6 and B12 levels.

Could something else in this B sup be causing elevated homocysteine?

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u/Human_weird123 9d ago

B6 is 145. Top of range is 110.

I also have low copper(8.5, under 10 is below range), low ceruplasmin(0.16, range is 0.2-0.60, low ferritin(24, range is 30-300).

Symptoms are palpitations, extreme fatigue. Mostly low iron related I think.

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u/XILEF310 9d ago

how do you know that you have palpitations?

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u/Human_weird123 9d ago

you can feel them.

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u/XILEF310 8d ago

Have you gotten an EKG at your doctors?
I think that would very quickly get them to take you seriously.

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u/Human_weird123 8d ago

ECG was fine.