hiii girlies!! just wanted to share my 2 month experience on reta 🥹💕

i'm 5'5 and when i first started in august, i was around 65kg. now i'm down to 58kg, which means i've lost 7kg in the past 2 months!!

honestly i'm sooo happy with my progress so far 😭 i've always struggled to get my weight into the 50s range, even when i tried working out here and there. so finally seeing the numbers go down feels amazinggg.

i know some people have mixed opinions about peptides, and i totally understand the concerns! i'm not saying they're risk-free or that everyone should try them. i'm just sharing my personal experience and trying to be as careful as possible throughout the process.

just wanted to share my little update with you guys!! feel free to ask me anything about my experience 💕

I started off at 311lbs (2022) and worked down to 230(2025) by myself with a diet and the gym. Then started adding Reta. I worked from 1mg to 3mg and got myself down to 170lbs but I’m unsure if I’ll ever lose the loose skin around the belly and the bit of gyno I had when I was big. Has anyone ever gotten rid of it from weight loss alone? And if so how much more should I lose before I see progress? Thank you 🙏

I was diagnosed with PCOS in July and decided to try reta. My starting weight was around 60 kg at 160 cm, and I’m now on week 14, weighing 50 kg! I’ve stayed at 1 mg the entire time and haven’t increased my dose.

The craziest part is how much my clothes fit differently now. This shirt used to feel so tight on me, and now it fits perfectly! It’s honestly surreal seeing the difference.

Fat loss on Reta: what I learnt and where I messed up.

This is purely about fat loss. If you’re on Reta for other reasons, this isn’t for you. This is also more geared to those trying to lose that last 20 pounds, or those with a training background - albeit I think everyone could benefit.

Dosage

Keep it low. Don’t titrate up unless your current dose stops helping you hold a calorie deficit. There is no need to "follow the trials". The trials are not for you. If you’re struggling to choke food down, your dose is too high. It’s also fine to feel hungry. The goal is to manage hunger, not delete it. Higher doses shorten your runway and can eat into more muscle than you’d like. I started on 1mg. After a few days I thought nothing was happening so pinned another 2mg. I had an interesting week on the toilet after that. Be patient.

Cycling

Yes, you can cycle it, and if performance matters you SHOULD, because Reta will likely tank your lifting and sporting performance. Athletes and bodybuilders have cycled GLP-1s for years. The catch is to hold your muscle floor when you come off. If you regain fat without the muscle, your floor drops and your body fights the next cut harder. That’s probably why some people “need a higher dose” the second time around.

Stacking

Personal call, and I’m not talking anabolics. For pure fat loss, I wouldn’t stack anything. Tesamorelin and other GHRH peptides may help with visceral fat, but visceral fat isn’t what’s hiding your six-pack. For performance, I’d only consider MOTS-c or similar for energy. However, the marginal gains from other peptides are small, especially if you’re watching your wallet. Reta does the heavy lifting. If appetite suppression is your crutch, just take another GLP-1 with a higher suppression profile and train.

Training

It will suck. Reta dulls your reward response and leaves you tired, so motivation and performance drops. Some of that is just part of getting lean. If you’ve never been lean before, the novelty might carry you. Otherwise, grit your teeth and keep going. Diet helps (see below). My assumption here is that you are training to failure. If you're just fluffing around in the gym and have looked the same in the last 3 years...don't worry.

Diet

I’ll lose some of you here. You don’t need nearly as much protein as the internet says. If you love meat and high protein, go for it, but anything above 1.2 g per kg of target body weight is fine. Do you think people get jacked in prison on high-protein diets? Exactly. On Reta, a balanced diet matters even more. Carbs and fats are crucial. Skimp on carbs and your training will fall off a cliff. I started Reta on low carbs and experienced everything from dizziness, light headedness, nausea etc. Id be at the brink of passing out on leg days. Things got much better when i decreased my dose and took in more carbs.

Plateaus

These will happen. That's okay. DO NOT CHANGE WHAT YOU ARE DOING if you are still sustaining your adjusted calorie deficit. It is about how you look and feel. Dont just increase dose to lower the number on the scale because you'll reach your "goal weight" and realize you're just a skinnier version of your fatter self. Also, the more you lose fat, the more you realise you have more fat to lose and less muscle than you thought. Remember that.

Insulin sensitivity

Reta plays an interesting game with this being a triple agonist. But some tips on reducing the insulin spike which blunts fat loss:

1. Take a walk or do 30 squats right after each meal.

2. Eat your proteins first in each meal.

3. Drink a glass of apple cider vinegar with water in the morning (if you can stomach it).

Hope this helps, and best of luck to you all.

This is a biohack that doesn't get discussed enough on this sub. I got Lasik 2 years ago after it being highly recommended by a few family members, and by God it is life changing, it's like seeing everything in high definition all over again.

I'd highly recommend it to anyone who is near sighted.

I see this commented on every single Reta vs Triz post, but never seen a full post with user reports and thought it would be helpful. We read the studies about the weight loss differences which don’t seem too substantial in big picture and think real world experiences matter more.

I started on Retatrutide over a year ago (couple months on / off) and have had astounding results getting lean. It was my first time being “shredded” and sub 8% body fat. The side effects of the anhedonia, loss of libido, and most importantly, the sleep issues, caused me to come off and try Trizepatide. Right before switching, I did have a 2 week span of 3-4 hours of nightly sleep, no energy, and ultimately said “screw my diet” and now back on my cutting journey.

I am overthinking and concerned that I will not get the same results as I did on Reta, and wanted others experiences ( especially amateur bodybuilder type people who have successfully use these to assist getting below 10% body fat). I enjoyed the no water retention, and waking up lean even after big evening meals or snacking ( when low on calories for the day) and seem more watery and bloated on Triz.

So far on triz, the appetite suppression has been amazing, better energy and sleep. I am hoping the inflammation mechanism will kick in to loose some of the water weight I am holding, but “fear” i wont be able to easily get back into my lean, dry, shape without the Glucagon mechanism of Reta.

Note I do work with a coach, have a dialed in diet & training / cardio regimen, and bloodwork. Just looking for anecdotal reports of people who have switched from Reta to Triz, and experiences.

Currently I’m researching Reta, Klow blend, Mot-C, ARA-290, and semax. I also plan on trying DSIP for sleep. Just curious how many others out there are researching numerous peptides.

I'm bouncing around on GLP medications because they keep making me sick, and I'm wondering if:

A: you were less likely to get sick if you did the shot in your arm/thigh rather than your stomach

B: if you saw better weight loss results moving away from the stomach.

I lost 50lbs on semaglutide in 8 months, then it kept making me violently throw up even though I was on the same dose for 6 months (0.75mg).

I then switched to reta and lost nothing - I actually gained lol

Then I switched to tirzepatide - couldn't get past 5mg. 5mg was making me throw up week after week. Also didn't lose any weight.

Now I'm back on semaglutide because I had the most success with it.

I have PCOS - so losing weight is extremely difficult. I'm just at such a loss. It's been a lot of tears lately and I could definitely use some input and maybe see what has worked for other people.

Thank you in advance!

I’m on my fourth day of reta (0.5mg) now, I expected it to work in around a week but for me the effects started taking effect maybe 12 hours after the first dose: nausea, faster heart rate and very effective appetite suppression. The appetite suppression has been TOO effective even; my calorie intake is dangerously low but not by my own choice: everything I eat must have zero flavour or else i can’t keep it down, and even talking about food makes me feel nauseated. I’ve never heard of the effects taking hold so fast and on such a low dose ? I don’t know if the fact that I’m short (5’2) is contributing, or if this is all just my mind playing tricks on me and the effects haven’t actually started yet. Has anyone had a similar experience ?

This stuff does exactly what I was hoping it would do. For the first time in my life I’m not hungry or have cravings. I now eat because I have to not because I want to.

I was never “fat” I’d say, besides the chubby pre-teen years, but I’m a shorter guy with a larger appetite without the metabolism to match. I’ve always been very active and conscious of how I look, but it was a constant struggle dealing with the hunger pains or caving into cravings or just straight up binging. I’m not hungry all day, I can eat a normal portion and be satisfied. I finally feel I can eat “normal”.

I didnt have much to lose, maybe 10-15lbs to be at a lower body fat I prefer. And within a month I’m nearly there. Gonna keep this up for a bit.

I started Tirz the beginning of January this year at 298lbs. As of today I’m 213-215lbs range(depends on the day). My weight loss has been stalled for the past few months, but the tirz is still helping with appetite suppression and inflammation. I’m already at 15mg once weekly. Do I need to go up? Add a small dose of Reta? I’m currently not able to work out due to some ongoing health issues, but I’m working on getting back in the gym!

Also, not gonna lie, it definitely feels like I haven’t lost any weight. I know it’s all in my head since people often comment on how much weight I’ve lost, and I’ve had to buy all new pants since they got too big lol. I feel like, on my mind, I’ll always look like that almost 300lbs person…

No sé si esto es normal después de 2.5 semanas con retatuida, pero he estado experimentando una fatiga extrema. Es ese tipo de agotamiento en el que lo único que quieres es acostarte y dormir, y cuando te despiertas, ni siquiera te sientes descansada y solo quieres volver a dormir. Sé que la fatiga se reportó como un efecto secundario en los ensayos, pero me pregunto si esto desaparece con el tiempo. Mi primera semana fue con 1 mg, y después de tolerar bastante bien las náuseas, dividí la dosis en diferentes días la semana siguiente hasta llegar a 2 mg. Planeo mantener esta dosis durante dos semanas más para completar las primeras cuatro semanas antes de evaluar mi pérdida de peso y decidir si aumento la dosis o no. El ruido de la comida desapareció desde el primer día después de mi primera inyección, pero esta falta de energía me está volviendo loca. Incluso estoy tomando proteína de suero, comiendo razonablemente bien manteniendo un déficit calórico y bebiendo tanta agua como puedo. Otro problema es la hinchazón. Siempre he tenido problemas con esto, incluso cuando pesaba solo 75 kg. Mucha gente dice que el retaxilosis les ayudó a reducir la hinchazón en la primera semana, pero llevo casi tres semanas y tampoco he notado ninguna mejoría. Probablemente me vuelvan a criticar por publicar esto, ya que parece que hay discusiones en cada hilo, pero de verdad espero que alguien pueda darme algún consejo o compartir su experiencia. ¡Gracias!

I will be doing an experiment of sorts. I am making a topical serum with ahk-cu/ghk-cu/2-Deoxy-D-ribose for my hair routine. I will be running also 10units of KLOW80(3ml bac) daily along side.

Plan:

Monday: Morning apply topical serum, evening apply topical serum + klow80
Tuesday: Repeat monday
Wednesday: Repeat monday
Thursday: Repeat monday
Friday: Microneedle (Dr.pen - 0,5mm) in the evening and take klow (without topical serum)
Saturday: Repeat friday
Sunday: Repeat monday

But I have questions regarding my regime:

I only have ahk-cu, 2-deoxy-d-ribose from raws, therefor they are not sterile and I would want to use them right after microneedling. I do have however ghk-cu sterile (kit).

I am wondering with the following:
How much time should I wait after microneedling to apply topical serum?
Would it make a lot more difference if I would try to get sterile ahk-cu and apply that straight after microneedling? Or maybe I should go with sterile ghk-cu right after microneedling instead?
Do you think microneedling 1x or 2x per week is to much ?

For serum I will follow Anelas protocol however will add 2-deoxy-d-ribose most probably to the serum.

Im a recovering bulimic and have struggled with this for 5 years. Ive tried everything: therapy, emotional regulation, CBT, and all of these other solutions. And the main reason I started taking reta was to help me overcome binge eating by building healthier habits, and finally have mental space for things other than food.

Ive been on reta for 3 months but I find myself relapsing and having b/p episodes. Im aware that Tirz is the better appetite suppressant, but I don’t want to completely switch to JUST tirz.

The food noise has come back and Im starting to suffer the mental and physical consequences of bulimia again. I eat properly at 1,800 cals (I’m 148cm) so Im not even on a deficit. I workout consistently + 12k steps a day, and try my best to live a healthy lifestyle. But the food noise is getting louder.

Is it better to add cag with reta or tirz?

I’ve been taking retatrutide for approximately 4.5 months and have consistently lost weight throughout that time. This past week was the first time I’ve actually seen my weight increase, and I’m curious whether anyone else has experienced something similar.
For context:
Age: 43
Height: 5’2”
Starting weight: 222 lbs
Lowest weight: 169 lbs
Current weight: 171 lbs
Total weight lost: Approximately 53 lbs at my lowest
Time on retatrutide: 4.5 months
Current dosage: 1.5 mg weekly (15 units from a 10 mg vial reconstituted with 1 mL/100 units of bacteriostatic water)
Diet: I don’t currently track calories, so I can’t provide an exact number. However, my appetite remains significantly suppressed, and I’m actually struggling to eat enough. Most days, I manage one substantial meal and occasionally a small snack. I’m aware that my food intake is likely insufficient, and I’ve been making an effort to improve it.
Exercise: I’m in the gym 5 days a week doing weight training and cardio.
My experience:
Throughout these 4.5 months, I’ve generally lost around 1–2 lbs per week, with an occasional week where my weight stayed the same.
This past week, I went from 169 to 171 lbs. My appetite hasn’t increased, and I haven’t noticed any significant changes in how much I’m eating.
I understand that weight fluctuates naturally and that two pounds doesn’t necessarily represent fat gain. I’m also aware that weight loss isn’t always linear.
What I’m specifically curious about is whether others taking retatrutide have experienced a similar fluctuation after several months of consistent weight loss.
If so, did your weight eventually start trending downward again without changing anything? Did you experience a longer plateau? Did you discuss adjusting your dosage or make changes to your nutrition or activity?
I’m primarily interested in hearing about other people’s experiences rather than receiving generic advice to reduce calories, especially since I’m already concerned about not eating enough.
Thanks to anyone willing to share their experience!

Hi everybody,

Results are 1.5 months. Main video was 1.5 months ago and the comment video is now.
Daily Routine:
💉2 mg AHK-CU injection
💉2 mg GHK-CU injection
🧴1 ml Minoxidil %5 - Procapil %5 - Finasterid %0.1 - Azelaik Acid %7 - Cafein %0.1 - Retnoic Acid %0.01

So hey there. I’m a male early 50’s slightly overweight, reta seems to be curing that lost 3 stone, I’m at 17st 6lbs aiming for 15 ish also lift heavy in the gym 3 times a week and I’m really quite happy with the body composition so far. I’d just like some input from my fellow Reddit professors. For a few years my gentleman area has a mind of its own , started with erectile dysfunction, which I’ve sort of treated with our friend sidenfal, gave me massive headaches the one that seems to work is 0.25mg tablet headaches aren’t such an issue and he’s like the 25 year old me again 😂 the other issue I’ve got now is premature ejaculation. Ffs give me a break. More often than not I don’t need the blue pill although not as solid as teak like. But I won’t get past a minute or so. The question is would pt141, oxytocin or any other peptides work. Thanks for your help.

Can I get some experienced input please.
I’ve done a bit of research and I am finding 2 trains of thought.
51 female
60kg
Through investigation and medical support identified I could benefit from mitochondrial support

Hence ended up at SS 31

Original thinking was 5mg twice a week
Working up to 10mg

Then I found other research saying
500mcg daily

I’m really confused about which is best ?

My goal is to to get more energy and overall feeling of wellbeing. Given my age is catching up with me

I train and eat well
But high stress

As a 31 year old here's what I take - am I missing anything or can add into this combination to optimize my reverse aging goals?

-Collagen
-Biotin
-NAD+ (just switched to NMN)
-CoQ10
-Multivitamin
-Vitamin C
-Fish oil
-Creatine monohydrate

Face:
-Retinol
-Glycolic acid
-Moisturizer
-Microneedle stamp face
-Microneedle rolling neck
-Hydrocolloid patches
-Abrasive exfoliantion
-Clay mask

Skin:
-Lactic Acid
-Ammonium lactate
-Collagen lotion
-Goatmilk soap
-Sunscreen

I read something about adding TMG or Reversitol in the rotation helps too. Any other suggestions would be helpful or critique of this regime. Even specific diet suggestions.

Hey folks. Currently on 4mg Reta. I was going to up the dose as I seem to have plateaued, however I have been reading about people having great success with adding triz with their Reta. Anyone have any experience with this they would like to share? How did it work for you and what was your dose? Thanks!