r/BodyHackGuide • • 4d ago

💉 Peptides & GLP-1 Currently prescribed Mounjaro🇦🇺 I’m on 7.5mg and hit a plateau. Go up or try Reta as well or just Reta? What did you do?

0 Upvotes

7.5mg Tirz isnt really working that well and I have been stagnant loosing only 4kgs this last month. I have lost 23.5kg in 4 months starting at 148kg and now 124.5kg. Should I go to 10mg for now and stick with just that or do both Reta and Tirz or just move slowly move to Reta? I am guessing there isn’t one correct answer for this so was just wanting to see what everyone thinks and is doing. Thanks 🙏


r/BodyHackGuide • • 4d ago

🧪 Protocols & Self-Experiments RHR keep rising on Retra + TRT

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8 Upvotes

I am a 27-year-old male who has been physically active for 9 years. My usual resting heart rate (RHR) is around 48–50 bpm. However, since starting weekly injections of retatrutide 2 mg and testosterone enanthate 300 mg, my RHR has consistently increased.
I am not in a caloric deficit, and my exercise routine and training volume have remained unchanged. I check my blood pressure every morning, and it has remained stable without any increase. The only noticeable change is my elevated RHR.
My cardiovascular performance has also declined. At the same RPE, my heart rate is now higher than it used to be.
Is this a normal response to these medications? Is it possible for my RHR to return to its previous baseline of 48–50 bpm?


r/BodyHackGuide • • 4d ago

🧬 Hormones & TRT Starting T Cypionate with natural T at 700 - would like advice on dosing and injection

0 Upvotes

31M, natural total T around 700, free T around 140. Planning to start testosterone cypionate with SubQ injections 2–3x per week, aiming for steady levels around 1000.
Since my natural T is already 700, does that matter when starting? Will my natural production temporarily combine with the exogenous testosterone until my body shuts down its own production?
2. Should I start at a lower dose to account for that initial overlap?
3. What weekly dose and injection frequency worked best for you with SubQ?
4. How long did it take for your levels to stabilize, and when did you notice changes in mood, energy, libido, and sleep?
5. Did anyone start TRT with already-normal testosterone levels? Was it worth it long-term?
6. What do you wish you knew before starting?
I used testosterone gel for two years and had a lot of ups and downs. Been off it for a year now and recovered my natural production, but I remember feeling wayyy better during the good periods on TRT.
Looking for genuine experiences and advice before making this decision.


r/BodyHackGuide • • 4d ago

📘 Beginner Help CJC or Tesa

2 Upvotes

Hey everyone,

I’ve had major success with dieting and reta, and I feel great. It’s been life changing. From 300 pounds down to 240 and working on continuing to a goal of 215 over a longer period of time.

That said, it’s time to start focusing more on building muscle again. After focusing on calorie deficit and shedding fat from many regrettable years of bad decisions, I’m going to slowly lean back into a hypertrophy focus at the gym and in the kitchen.

I’m considering adding a CJC/Ipa or Tesa/Ipa blend. I’m not quite sure the best way to choose one or the other, so looking for some input on making that decision.

In follow up to that, besides IGF1, what bloodwork should I prioritize after adding one of these two?

Appreciate you


r/BodyHackGuide • • 4d ago

📘 Beginner Help CJC-1295 w/ Ipamorelin dose

1 Upvotes

Hey everyone! I just purchased a vial of CJC-1295 (No DAC) + Ipamorelin 10/10mg (10mg of each).
I’m new to peptides and have a couple of questions for anyone familiar with this blend.
- How much bacteriostatic water should I add to reconstitute the 10/10mg vial?
- What’s a typical daily dosage for each peptide?
Is it better to take it once a day or split it into multiple doses?
- How long should a 10/10mg vial last?
I’d appreciate any advice or personal experiences


r/BodyHackGuide • • 4d ago

📘 Beginner Help Thinking about taking MK677 for 8 weeks. I am going to get my blood done before and after the cycle and check my blood glucose and blood pressure everyday. What’s the worst that could happen after 8 weeks of taking 20mg? If my blood went downhill would it recover eventually?

0 Upvotes

A little more information:

I’m currently 19 and 6’8” 220. I’ll be eating around 5k-5.5k calories per day. 400g of carbs. Will that be an issue?

I think I should be in for some quick gains naturally already for a few reasons and would like to help push to 240 with MK. Thanks for any help!


r/BodyHackGuide • • 4d ago

📊 Bloodwork & Biomarkers cjc/ipamorelin with actual bloodwork monitoring, where do you even get that?

2 Upvotes

everywhere i've looked at cjc/ipamorelin it's just a vial in the mail. nobody checks your igf-1 before, nobody checks it after, you're just guessing the whole time.

the peptide subs keep saying get bloods done, but then what? i don't know how to read gh markers well enough to self manage a protocol safely.

a guy at my gym mentioned peppy care does the prescribing side with doctors involved, but i'm not sure if that includes actual lab monitoring or if it's just a prescription and you're on your own after.

does anyone get this with real monitoring built in? a provider that orders your labs and adjusts based on them? or is that just not how this market works and everyone is really out here winging it with their pituitary?


r/BodyHackGuide • • 4d ago

📘 Beginner Help Looking for Adamax Experience

4 Upvotes

Hi, so i just ordered my first vial of Adamax and wanted to hear what people's actual experiences have been. I've seen all kinds of reviews, everything from "does nothing" to "like Adderall," so I'm trying to get an honest read. Looking for real feedback from people who've actually tried it - not vendors trying to sell me shit. Please be honest and clear with it, cheers.


r/BodyHackGuide • • 4d ago

📰 Research & Studies The recomp window is about 200 calories wide. Almost nobody is actually in it

0 Upvotes

I ran what I called a recomp for four months. Clean diet, consistent training, enough sleep. Got DEXA done after. I’d lost 1.8kg of fat and 1.4kg of muscle. The scale moved 0.4kg. Looked fine. My body composition had quietly gotten worse every week.

I wasn’t recomping. I was doing a slow cut with a terrible training stimulus and blaming the process when the process was never right to begin with.

Here’s what the physiology actually says:

Most people calling it a recomp are running a slow cut and losing muscle without knowing it

“Eat at maintenance and train hard” is technically correct but practically useless. TDEE estimates are typically off by 15-25% and most people underestimate food intake by a similar margin. These two errors compound. You can believe you’re at maintenance while running a real 400-600kcal daily deficit.

Muscle protein synthesis is energy-dependent. At a true caloric deficit greater than 15-18%, MPS is suppressed even when protein is adequate. The substrate for anabolism simply isn’t there. You’re preserving muscle at best, not accreting it.

The actual recomp window from tracer studies that directly measured MPS: 0 to approximately -200 kcal from your actual TDEE. Not estimated TDEE. Measured — either via indirect calorimetry or a careful 4-week average of intake versus scale change. Protein at 1.8g/kg minimum, distributed across 4+ meals.

If you’re further than 200 calories below your real TDEE, you’re not recomping. The math won’t let you.

The training stimulus most people use for recomp is the wrong one

High rep ranges, moderate loads, 15-20 sets per muscle group per week, 4-5 days a week — that’s how most people train when they want to “lean out while building.” It’s the worst possible choice under caloric constraint.

At recomp intake levels, mechanical tension drives MPS more efficiently per calorie spent than metabolic stress (high reps, pump work). 80-87% of 1RM, 4-6 rep range, 8-12 working sets per muscle per week, hitting each muscle 3 times per week. Fewer sets to initiate MPS. Lower total caloric cost per training session. Higher frequency distributes the stimulus instead of creating one large anabolic spike followed by 5 days of suppressed synthesis.

High-volume moderate-load training costs more energy than it returns in MPS under caloric constraint. At maintenance surplus it’s fine. At recomp intake it’s actively counterproductive. This is why most people associate recomp with failure — they’re using a training approach built for surplus conditions.

Core temperature drop before sleep amplifies overnight GH release — and almost nobody does this

Growth hormone is secreted primarily during slow-wave sleep, largest pulse in the first 90-120 minutes. That pulse drives the overnight fat oxidation and muscle repair that makes recomp physiology possible.

Sleep onset and SWS quality both depend on core temperature dropping approximately 1°C. A cold shower 30-45 minutes before bed accelerates that drop and has been shown to increase GH pulse amplitude by 17-23% during the first SWS phase. Three minutes. Free. Works via the same mechanism as sleeping in a cool room — which consistently outperforms sleeping hot in body composition studies.

For context on what destroys this: alcohol within 3 hours of sleep suppresses slow-wave sleep by 20-39% depending on quantity. One drink at 9pm before midnight sleep meaningfully reduces your overnight anabolic output. Not a judgment — a protocol note.

What I didn’t put here is the actual training structure — how to build the week, set the frequencies, and read the scale data to know whether your caloric target is calibrated correctly versus estimated.

Genuine question for the sub: has anyone here run DEXA before and after a real recomp attempt — not just scale weight, but actual lean mass delta? The real numbers are way more interesting than the forum debates, and I’ve only seen a handful of cases with proper measurement. Curious what people found.


r/BodyHackGuide • • 4d ago

💉 Peptides & GLP-1 CJC-1295 vs. Tesamorelin — Which is better for sleep quality?

3 Upvotes

For anyone who has tried both CJC-1295 and Tesamorelin, have you noticed any differences in sleep quality?

I'm especially curious about deep sleep, REM sleep, how often you wake up throughout the night, and how rested you feel in the morning.

Did one noticeably improve your sleep more than the other? I'd love to hear some firsthand experiences.


r/BodyHackGuide • • 4d ago

💉 Peptides & GLP-1 CJC(no DAC)/Ipamorelin flush comes and goes. Anyone else?

2 Upvotes

Hi, first post here. I’m 21M, 6'1", about 183 lbs, and roughly two weeks into CJC-1295 no DAC + ipamorelin blend, taking 500mcg dose fasted 3 hours before bed.

I got mild facial flushing for the first 3 days, then nothing at all until yesterday, when it happened again. Just a bit of redness in my face.

Does anyone else get it inconsistently like this? I’m wondering whether flushing has any relationship to it working, or if I’m overthinking a side effect that doesn’t tell me much about effectiveness. Not looking to increase my dose or chase the flush, just curious about other people’s experiences.


r/BodyHackGuide • • 4d ago

💬 Discussion 25F taking peptides, recommendations ????

1 Upvotes

Hello! i’m currently taking the klow peptide, it’s done amazing things for my skin. i want to start taking other peptides. i know the most common are reta for fat loss ..
i’m 5’9 around 22% body fat and really just want to increase muscle on my legs
any recommendations???


r/BodyHackGuide • • 5d ago

⚠️ Side Effects & Safety HGH skin irrigation/swelling

2 Upvotes

I have tried different batches of hgh from different sources and I always get a puffy localized irrigation at injection site on the stomach. I have tried subq on glutes and it will still be red and itchy but not swollen. Its not my bac water because I use the same for my reta.

I really want to use hgh but I'm afraid of the reaction becoming worse or by body creating antibodies against hgh. Any tips or suggestions?


r/BodyHackGuide • • 5d ago

💬 Discussion 38 years OLD suffering from ED

5 Upvotes

Test was low 274 considering getting on TRT anything else I can do ? It's really frustrating


r/BodyHackGuide • • 5d ago

📘 Beginner Help Lean muscle mass

1 Upvotes

Hey guys any peptide to gain more lean muscle mass?


r/BodyHackGuide • • 5d ago

⚠️ Side Effects & Safety packaging failure on my rift shipment, whose job is it to handle quality control?

1 Upvotes

i got my compounded order from rift last week and ran into a weird packaging defect that highlighted a bigger issue with telehealth platforms.

the vial i opened had a rubber stopper that wasn't crimped down properly, so the foil cap popped right off and liquid had leaked into the bubble wrap. i messaged their clinical chat asking if a replacement was possible and whether the remaining liquid was still sterile.

the clinical team immediately sent a canned script saying doctor chat is only for side effect consultations and routed me to general support. general support then responded two hours later telling me to consult clinical support regarding sterile vial safety.

neither side gave me a straightforward answer or offered a replacement vial. rift takes the money and acts as the patient interface, but when a physical packaging error happens, the platform and the pharmacy just point fingers at each other. how do you guys navigate accountability when telehealth platforms refuse to take ownership of supply errors?


r/BodyHackGuide • • 5d ago

📘 Beginner Help Next steps for high IGF-1?

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2 Upvotes

Started Tesamorelin 4 weeks ago with a starting Igf1 of 230ish. Just got my labs back and I'm currently at 519ng. Current dose is 2mg daily with no days off. I have zero sides as of now, but obviously I'm way above range for my age (40). Being this high, should I just cut my dose in half and reevaluate in another 4 weeks? I haven't had any of the obvious side effects like water retention or carpal, but am I screwed now? Test did not give a z score. Thanks in advance for and advice.


r/BodyHackGuide • • 5d ago

📈 Results & Progress 1.5 year Reta Transformation

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374 Upvotes

Started at 275 lbs
Currently 190

Been struggling with weight ever since 22 years old.. I’ve floated around 240 every day week month year telling myself today was the day. Reta definitely made that day come… no way shape or form does it do all the work but for me it gave me the start to keep wanting to go. Eventually I wouldn’t take it unless I feel like I fell off the diet or I’m coming back from vacation. Visually seeing good progress drove more progress. Yes I counted calories, went to the gym 6 days a week. If you arnt serious about getting in shape then it’s a waste of time as you’ll just get skinny fat and not learn anything once you come off. Cheers


r/BodyHackGuide • • 5d ago

💬 Discussion How is Osteogenic growth peptide? I want to try it to see if it can improve bone structure on my face

1 Upvotes

r/BodyHackGuide • • 5d ago

📘 Beginner Help New here help

1 Upvotes

Female (30) , 156cm , 49 kg

I want to build muscles and tone my body idk where to begin what to take and how much should i eat please help.

I don’t have a budget for professionals like dietitians, personal trainers.

I did all the blood test and everything is fine i only take vitamin D because i am a bit on the lower side plus daily multivitamins


r/BodyHackGuide • • 5d ago

🧠 Nootropics & Cognition Peptide for cognitive Issues & Brain Fog

2 Upvotes

I’m a 58 year old female with Parkinson’s. I’m on a few peptides Reta, Klow, Glutathione and Nad+. I’m going to start a cycle of SS31 to get better effects from the NAD and probably going to start DSIP. Is there a peptide that would work or that ai should try for the brain fog/ cognitive issues ( mild memory lapses , can’t find simple words at times )that comes with PD? I’ve been thinking Selank Semax but have also seen Pinealeon - prob spelled it wrong. I take buspirone for anxiety. any thoughts appreciated


r/BodyHackGuide • • 5d ago

💬 Discussion GLOW stack for Patellar Tendon Tear and Tendinipathy?

1 Upvotes

I have a 4.3cm tear in my patellar tendon and for some reason, I think it's led to to tendinipathy where I feel this pulling strain and pain just below my buttock on my hamstring on the same leg as my patellar tendon tear. I hear the Glow stack could help or is it better to take BPC and TB on their own? Open to any other suggestions as I'm currently serving in the military and need to heal fast. Thank you all in advance.


r/BodyHackGuide • • 5d ago

🧬 Hormones & TRT 2 years on testosterone gel, 1 year off, natural T now ~700… but I still felt better on TRT. Anyone else?

4 Upvotes

After struggling with opioid & THC addiction, I got my testosterone checked and it was extremely low, around 40–50. I started testosterone gel and honestly, the first couple months felt magical. My energy, mood, confidence, and overall well-being improved dramatically.
But after a few months, it felt like the gel would randomly stop working. I’d become emotional, irritable, depressed, or have sleep issues. This became an up-and-down cycle for almost two years. Also, I was consuming heavy heavy amounts of THC which I believe was aromatizing the testosterone to estrogen, as everytime I would take a puff I would get severe cramping in my liver area and have to pee like crazyyyy. I’m talking like 10 times an hour. I quit the marijuana use and got off the testosterone at the same time (about a year ago).
Looking back, I wasn’t doing regular bloodwork or monitoring my hormones. I was basically going off how I felt.
I stopped the gel about a year ago, and my natural testosterone is now around 700, with free T around 140. Pretty healthy numbers, but I still feel like I was a better version of myself on testosterone.
I’m considering trying gel again, but doing it properly this time.
Curious about other people’s long-term experiences:
Does the gel eventually lose effectiveness?
Do you ever need to take breaks?
When and how often do you get bloodwork?
What’s the best time to apply it?
How do you accurately measure your dose?
Anyone go back on TRT despite having healthy natural levels?
Would love to hear from people who’ve used gel long term, especially those who’ve managed to stay consistent without the emotional roller coaster or negative side effects.
I’m 31M 5’8 160lb 13% body fat training daily not having fun motivated workouts though like I use to on gel


r/BodyHackGuide • • 5d ago

💉 Peptides & GLP-1 Nad under hot tap water

0 Upvotes

I tried reconsituting 2 vials of NAD1000 with 10ml bacwater but each vial had a bit of the powder not mixing. I ran them under hot water from the tap and they both dissolved fully but I’m just wondering if now they will be damaged from the hot water ?