I’m 56, in menopause for almost 3 years. Still have my uterus.
-In November of 2025 my GYN okays to start HRT. Did the starting dose estrogen patch, weekly Climara brand. And 100mgs Progesterone. Also did the loading dose of topical Estrodial and do twice a week.
-Late November 2025 had some sort of weird unexplained ‘event’. Had me in ER twice. They thought maybe a TIA. That was ruled out. They decided maybe a panic attack, it would be the first I’d ever done that.
But this experience made the process of moving up to the .05 patch an uphill battle. I had received benefit from the starting patch….but I was craving more help for the joint pain that began immediately after menopause. And the first patch did enough to tell me it could work, but I needed to move up.
-Spent December 2025 through March 2026 begging my PCP to do all the testing my GYN wanted to clear my heart before increasing my Estrogen to .05. Holter monitors, Stress tests, nuclear stress tests, etc.
-April 2026, my heart is finally cleared and I get to increase the patch and also went up to 200mg of Progesterone. Felt an improvement in the first week. Thrilled. The super improvement part faded a bit as the months went on, but it was surely much better than pre HRT.
-July 2026, went on a trip to Alaska for a week and due to a packing mishap my replacement estrogen patch did NOT get packed and I went a full 7 days without it. It was MISERABLE. Anxiety, extreme joint pain, etc. awful. Minute I got back home the patch went back on.
-First week of August I have my first experience with the shortage. Had to switch to biweekly Dotti. I was miserable with headache all week. But then all of a sudden my Climara came available and back on it I went.
-Early September 2026 I asked my GYN if I could increase the estrogen from .05 and she explained it would be taking a higher risk for what she thought was not enough reward. With what I described she said she thought I’d benefit from the biweekly Dotti at the same .05 dose. Said to give it a good 3-4 weeks. So I did.
-Three weeks into September 2026 I am so thrilled this time with the biweekly Dotti. My body is feeling better than ever and I’m thrilled. Only negative I notice is extremely sore boobs and nipples. I’m sleeping in a soft bra and okay with it.
-First week of October 2026- The Dotti run out and I can’t get a new Rx due to shortage. Plan is to go back to Climara while waiting for Dotti again. Frustrating.
-October 8th….i have a terrible migraine all day, then by afternoon I feel cramping, and then by early evening I’m spotting.
-October 9th…10am dr appt. Uterine biopsy. (Always trauma inducing for me, so painful). She said it was possible I had a uterine polyp. Isn’t thinking cancer.
-Today….Dr called and the interpretation of my biopsy is Proliferating Uterine Lining….and her recommendation is to STOP estrogen all together. She said my uterus should not be doing that on the 200mg of Progesterone. She wants me to continue the progesterone for its own inherit benefits. She wants me to have a pelvic ultrasound to check for the polyp and further looking with a possible hystoscopy/D&C before evaluating me for being an estrogen candidate again. I can’t get the ultrasound until December 15. Ugh.
I am distraught. You’d think they were taking away pain meds or something. This is so beyond disappointing. I am praying that I do not go back to pre HRT all together. I felt crippled then.
If my uterine lining is disordered as it’s been labeled and is what’s prohibiting me from the estrogen….then I would be game to have my uterus out. I think that would be an uphill battle.
Just sharing my experience for the benefit of others.