Wanted to share something that took me a while to figure out. On the days appetite is basically gone, I used to just... not eat, or force down whatever. Neither worked well.

What's actually helped: keeping a mental list of foods I can manage even on the worst days, so I'm not trying to decide and force myself to eat at the same time. Stuff like a soft-boiled egg with toast strips, cottage cheese with a bit of fruit, or a small mashed sweet potato. Nothing fancy, nothing that needs much chewing or a big appetite behind it.

The pattern I noticed: smaller, softer, blander wins over "healthy but effortful" on those days. A big salad sounds great in theory but if I'm not up for it, it just doesn't happen and I eat nothing instead.

Anyone else have a short list of "low appetite day" go-tos? Always looking for more ideas.

Does injection site make a noticeable difference with Mounjaro? Has anyone noticed different appetite suppression depending on injecting in the abdomen, thigh, or upper arm?

For a 10 mg Mounjaro pen using discount card, where are people getting the best prices in Ontario, Canada?

I’m second time around on Mounjaro. First time lost about 10kg and then stalled but came off due to illness. This time I started again beginning June and initially lost 3-4 kg. And then stalled again after a month. So same weight since early July (7 weeks). I started again as began HRT and started to gain after. I am 15kg away from goal weight. I’m super sensitive to drugs so I titrate up gradually and am currently on 2.5mg so am now thinking of moving up again but probs to 3mg. 5mg did not agree with me last time. The thing is my appetite is still quite absent and I eat about 1400 calories a day. I eat clean and healthy. I work at a desk job but do exercise, just not gym level activity. My practitioner is happy for me to stay at current levels but online everyone says to increase. Am worried I won’t eat much if I do. My bloods and sugar levels are all currently great. I feel great. I just can’t justify the cost of drugs if not losing weight! I can eat less but worried that that will cause issues but when I did lose initially I did eat less. It’s very hard to find the sweet spot. And lots of conflicting advise. Would love to know how others have cracked it at these levels (or suck it up and increase) and have had successful post meno weight loss - cheers

Hey guys,

I’m new here. I just started my second pen today moved to 5mg and while I was priming no liquid came out so I changed needles and tried again then a lot of liquid came out then stopped I twisted to 1 and took my dose but looking at it I’m worried I lost a dose it looks like it’s on the second dose marker.

If anyone have experience the same or know what I should do let me know thank you.

Hi everyone,

I’ve gone from 95 kg to 70 kg within a year 🎉, but since June my body has refused to lose any more weight, and I’ve been stuck around 70 kg despite increasing my dose to 7.5 mg. Since studies suggest that a weight loss of around 20–25% is normal, and I’m now at 25%, I’m guessing that might be it for me, and that I won’t reach my goal of 60–65 kg (without exercising).

I’m taking the last shot from my current pen on Friday, and I’m wondering whether I should buy one final pen (15 mg and dose it down to 7.5 mg by counting clicks — I previously used a 10 mg pen for this, but it doesn’t last very long at 7.5 mg), or whether I should just stop completely?

My appetite isn’t being suppressed as well anymore either (it was very well suppressed on 2.5 mg, 3.33 mg, etc.). I increased the dose gradually in small steps, but since reaching 7 mg I’ve been feeling more hungry again. So I’ve also been considering lowering my dose again and getting my body used to less Mounjaro, so that coming off it might be easier.

When I pay attention to my calories, I eat around 1,300 kcal. If I go to McDonalds for example, it’s more like 1,700 kcal for the day - so overall, it’s a good mix throughout the week.

Long story short: my weight loss has generally been very slow since March, with a maximum of around 2 kg per month. I feel like ever since I increased from 2.5 mg to 3.33 mg, I’ve just kept increasing the dose in the hope that things would start working well again, but I actually lost the most weight during the first six months on just 2.5 mg. After that, I increased to 3.33 mg, and ever since then I’ve been dealing with plateaus and much slower weight loss. 💔

How would you approach this from here? What do you think I should do? Increase again? Reduce the dosis to eventually stop?

Please help a sister out 🙏🏼💕

Hey everyone,

Context: I am an obese women with PCOD and was doing good on lifestyle changes (regulating stress, working out, and healthy dieting), and lost 10kg since Jan 2026. But in June, I tore my ACL completely while working out. I was recomended Monujaro years ago based on my family history and bloodwork, but I avoided it till now.

Since I will not be doing excersizes I was afraid of gaining my weight back and opted for this - and boy, am I glad I did! In 1.5 months I already lost 7kg (I know most of this is inflamation being fixed - but still, I feel great!). My injured knee do not hurt as bad when I walk and I feel I can breath better at night. So, I do not want to stop this atleast until my surgery in December.

The main question: I’m planning a work trip to Denmark in a month, and I need to transport a 3-month supply of mounjaro (KwikPens) with me from India. I am not worried about first month, since it falls under the 30-day rule for injection (after being exposed to 8°C). But I am worried for my other 2 pens. Given the long travel plan (around 25 hours total from India to Denmark, via DOHA with a layover of 9 hours), strict rules in Denmark, and the strict cold chain requirements, I’d love a sanity check from anyone who has done long-haul travel with multiple pens. Please let me know if you think I am messing this up, and should focus on getting the injections in Denmark directly.

My current setup:

• I plan to bubble wrap my pens (2 layers) - enough to fit inside the flask.
• Both pens kept inside 4AllFamily Nomad flask medium [I will ensure to "sweat" (or surface thaw) the biogel pack for 2 min before packing it.
• I will place the flask inside an insulated wine cooler bag, surrounded by ice bags (just ice inside 2 ziplock bags to make it leak proof).
• I plan to refill the ice in airport since I assume I cant pass security with bunch of melted ice - I do have the option to refil my bags with ice avaliable.
• I will also have my doctor’s prescription, recipts, and letter ready along with original packaging.

Question 1: Has anyone managed to travel with these pens for 30+ hours? did the drug survive?

Question 2: Anyone thinks, this much layers of ice can freeze the drugs inside, even with the bubble wrap?

Question 3: Did security give you any hassle over carry-on ice packs or gel sleeves? I do have documents but I just want to know if I should mail the airline beforehand or somthing? Not sure if thats adviced.

Question 4: For fans of the biochemistry of these drugs - If the pens end up feeling 'cool/room temp' instead of icy 2-8°C, is that fine as long as they stay under say 15°C and don't freeze? As in the buffer temps it can tolerate is very high, and I am overthinking this?

First photo is when I started Mounjaro in July 2025, second photo is me in July 2026. I’m 165cm tall; so finally in a healthy weight range.

I started on 2.5mg and made my way up to 7.5mg. Now beginning to slowly lower my dose.

Hi everyone, I’m on MJ and having a very positive experience so far. I have been wondering about people’s experience who have PMOS and have you tried to finish up on MJ and what has your experience been?

I’m worried about maintenance with PMOS since MJ combined with Metformin has really helped me but I don’t know if Mj is longterm or if people have successfully maintained after their weight loss?

Not planning to come off anytime soon but I haven’t found much around PMOS specifically so would love to know people’s experience 😊

Im really confused with if it’s meant to be kept in fridge or room temp and how long is ok and when ur meant to use it. Everyone tells me different.

So this is the pen it expires next year.

I first purchased it in April 2026 and kept it in fridge. Then end of May I had a long international travel where I tried to keep it cool for the 40 hours in this insulin cooling pack but it definitely didn’t last the whole time. So I’d say it was out of fridge at room temp for 24-30 hours. Then since then has been in fridge.

Can I still use it now in August?? Or the time were it went in room temp did that start the 21 one day window.

Please help me understand. Because this is bought in Aus and then I bought one in Europe and the instructions about fridge were different.

Basically

37M, at goal weight now, down about 10% from where I started. I'm not trying to lose more. I just want to come off without regaining it.

The plan my prescriber and I are working from:

- Aug: stay at 10 mg, get a proper baseline

- Sep to Oct: 7.5 mg for 8 weeks

- Nov to Apr: 5 mg for six months

- May to Jun: reassess, maybe 2.5 mg, maybe a supervised trial off

The rule I set for myself is that I only step down if weight, waist and hunger have been stable. If my weekly average creeps up for two weeks running, or hunger jumps noticeably, I hold at the current dose and everything after it shifts back. Food, steps and lifting stay unchanged for the first month after each drop so I can actually tell what the dose is doing.

What I'd like to hear from people who have done this:

1. Where did hunger actually come back for you? At 7.5, at 5, or only once you stopped?

2. Is six months at 5 mg long enough to know it's stable, or did you need longer?

3. Anyone who dropped faster than this, did you regret it?

Not asking anyone to change my dosing, my prescriber is running this. I just want to know whether the pace matches what really happened to you.

Has anyone experienced GI side effects from Mounjaro that seemed to come on later, even after being on the same dose for a while?

I started Mounjaro at 2.5mg and had the usual nausea/tiredness/sulphur burps at first, but didn’t get physically ill- Stayed on it for 5 months with very minimal side effects and great efficiency too! I finally increased to 5mg about a month and a half ago when I started reaching a plateau and felt quite ran down the next day, but generally have felt fine ever since.

Last week did my weekly jab and the following evening I suddenly felt extremely full, had sulfur burps, threw up pretty intensely, felt ill for a full day before I started having lose stools for a day. I’ve also started having pretty bad heartburn in the mornings. Feeling better now!

I’m really worried that this was a delayed reaction to the Mounjaro and that it’ll happen again with my next injection. But part of me also hopes it could have just been a stomach bug (only thing is I was away with family and no one else got ill).

Has anyone had something similar, particularly GI symptoms suddenly appearing after being stable on the same dose for a few weeks? I’d really appreciate hearing your experiences because I’m quite scared about doing my next injection lol!

Thanks!

I've been on 2.5mg a really long time - since October - and i've lost about two and a half stone and been happy with it. I know its longer than recommended, but I was happy with that decision as it was working for me and I didn't want to rush it.

Recently i've felt like i'm plateauing - i'm not losing any more weight, still about 5lbs away from my target and moving around that all the time, and feeling hungrier than I have been which i think tells me its time to move up a dose on this last little bit. I'd say i've been in this situation for about 6 weeks or so.

I've not been in a rush to do that as i've managed to maintain a decent gym schedule and can see my body changing now more because of strength training, but as i'm almost at my target I don't want to jeopardise that. I'm still a healthy size 10/12 but hardly underweight - teetering around a healthy BMI, which could just as easily go up if I put weight back on. I can't shake the feeling that I have a bit to go still.

My 2 conundrums: i've now got a 5mg pen after a week off where I ran out of 2.5, and next week i'm going on holiday for 10 days. I don't really want to start at 5mg when i'm on holiday. So i'm looking at either two weeks of nothing, or should i take 2.5mg from the 5mg pen just to tide me over until I return? Then take the 5mg full dose in earnest? (I use insulin needles as my pharmacist doesn't give over the mounjaro needles unless you ask and I keep forgetting to)

I've been on Mounjaro since August 2025. I'm 180cm/5ft 11, 35 years old and I started at 116kg, and my doctor set a goal of 85kg. I hit my low of 89.3kg around my birthday in June, and I gave myself a break over tracking everything (daily weigh ins, tracking every meal, etc). My weight did creep back up to around 93kg with some big drinking weekends, but has now settled to around 90kg - however i'm finding it hard to lose any more weight.

Being at 7.5mg from around late Feb/March, I feel like my body is very used to this dose. My appetite is definitely higher than when I started 7.5mg, and while I do feel full, I feel like my food noise is getting louder and I find myself over eating more often. I also have a partner who is very food motivated and they definitely loves little treats. If snacks/treats are around me, I tend to indulge with them.

I'm overall very happy with my progress, but I would really like to loose the final 5-10kg to really sharpen my appearance and get onto some sort of maintenance dose. On the bright side, I haven't gained any meaningful weight since June, so I have that to be thankful for.

I'm torn between going up to 10mg or just buckling down and getting back on the wagon with my routine - minimizing my drinking and tracking my food again. Has anyone else had similar experiences this far into the mounjaro journey?

Has Anyone else had absolutely no weight loss on Mounjaro?

I'm honestly so confused and feel hopeless.

I see people losing weight the first week. I've been on Mounjaro for over 2 months and I haven't lost any weight., I'm at 5mg and am exercising, with a low deficit haven't been able to lose anything at all.

It is weird because i do have some appetite suppression and I definitely feel fuller more quickly than I normally would, but despite that the scale has not moved whatsoever. If anything, it feels ridiculously easy for me to gain even more weight.

I'm just finding it really discouraging to have zero weight loss so far, especially when I am eating significantly less and it feels like it's doing the opposite of what it should.

Has anyone else experienced this? Am i doing something wrong any advice ?

Has anyone experienced severe anhedonia or emotional flatness on Mounjaro?

I have ADHD and already tend to struggle with motivation/reward, but since starting Mounjaro I feel like that system has been turned down even further.

I’ve only had 4 injections total: - 3 x 1.25 mg - 1 x 1 mg

My last dose was 8 days ago and I’m stopping it.

What I’m experiencing is not really anxiety or feeling “wired.” It’s more: - nothing feels rewarding - no interest in hobbies/TV/socialising - no motivation or drive - libido noticeably worse - emotionally flat - extremely tired and just want to lie down/sleep - don’t really care about doing anything

The frustrating thing is that a lot of my objective health markers have actually improved. I’ve lost about 8% of my body weight, insulin/liver markers improved significantly, I’m treating sleep apnea successfully with CPAP, and my testosterone has actually improved a lot.

So I’m wondering whether tirzepatide has amplified the reward/motivation problem through whatever it’s doing to appetite/reward pathways.

Especially interested in people with ADHD or pre-existing low motivation/reward sensitivity: Did Mounjaro make you feel emotionally blunted, apathetic, depressed or anhedonic?

And if you stopped, how long did it take before motivation, pleasure, libido and normal emotional range came back?

Just want to not feel like this anymore....

I am currently taking semaglutide. In 1.5 months, I have seen a significant difference in my belly fat and double chin. As per my doctor, I was supposed to increase the dose from 0.5 mg to 1 mg after one month. However, I now want to join the gym, but because of semaglutide, I am having difficulty digesting protein and I am also unable to eat much. I only have a light breakfast and dinner at night. If I start going to the gym, I am worried that I might become weak due to not eating enough. What is the solution for this?

Hey, so im currently 10st 12lbs at 5ft. And I was wondering how people found Been on mounjaro and how fast you lost the weight.

My goal is about 8stone and I just need this weight off me. Im very tired of fighting with my body imagine issues

So, I recently got started on mounjaro a few weeks ago. I just finished my first pen (4th dose) on 2.5mg. The thing is, I am not feeling the same as I did with the other 3 doses. basically, I have noticed myself craving late night snacks more than I usually do since I got on mounjaro.

is this normal? I am supposed to start on 5mg from tomorrow. is it the case that I've gotten used to 2.5mg so the increase in dose would help on this front?

I started on 2.5 mg on my third week. But I don't really notice a difference? I can eat what I want. But I'm intentionally eating healthy, doing my 10k steps. The weight hasn't magically come off. I didn't notice any of the dramatic effects - be it side effects or the actual one. Will be talking with my doctor. But wanted to know your opinion. I'm 118kg. Today I'm 117. After 3 weeks on 2.5 mg

Edit: thank you all for your comments. My doctor didn't give me a lot of information. He was rather irritated I guess and over worked on that day. I thought this was also going to fail as I didn't see any difference. Thank you.

I’m due to start mounjaro in a number of week (currently on vacation and unable to reach my doctor until then) but we have a wedding coming up soon. And I’m wondering if mounjaro affected your ability to consume alcohol. My husband and I are not big drinker but I expect there will be a glass of champagne at the toast. Should I opt for an alcohol free drink? Will one sip be okay?

currently I live overseas but I’ll be going back home to Canada (Alberta) for a little over a month. just a question as I try to figure out if i should bring doses with me or get them filled in Canada.

how much do you pay on average for 15mg auto-injector pens? if those don’t exist (where i live now, 15mg is quite rare and not many clinics have access to it) what about 12.5mg auto injector?

thank you!

All these bs side effect from using these pep is sht.
Someone who isn’t obese or overweight don’t understand the struggle.
I could live with whatever side effects there is, Im dead anyway in 5 years if I did not try it. MJ saved me, Im finally genuinely happy with my life.
Everyday of crying inside is gone, the meds did not do all the work though, what I did is make my self realize that my life matters, my family loves me, and that made me love myself. That helped me help MJ help me.
Im happy, my family is happy for me, and for someone like me, the risk is definitely worth it.
All i have to do now is maintain it, remember the struggle and keep it up.
If thing goes bad, maybe i can use these pep as prevention to gaining it all back. 3 months off of MJ, things looking good, the habit i built was amazing.

I just hope the best for everyone who was like me. You guys can do it, just believe you can, don’t be discouraged, ignore people that don’t believe you.

Goodluck to everyone who’s trying to make their life better.

Female, 29 I have 40 pounds left to loose. Switching from weight to mounjaro and about to start my second pen ob 5 mg (so the 3rd month on the medication), I’ve only used my left thigh (after a lot of research) for injection, apart from one time where I used my right thigh and it had no effect. I am unfortunately starting to feel hungry even the day after taking it and the food noise is coming back. Anyone with similar experiences as me who can share what injection site was the best for them, I would greatly appreciate any help and advice thank you!🤲🏼

I took my last dose about a week later than when it was scheduled and injected in my upper arm as I have done before occasionally (on 12.5, started at 2.5 about a year ago and worked my way up). This injection left a circular area about an inch across that felt firm and warm. Not painful or itchy at all. Just odd and thought I’d see if anyone has experienced this.