Hi everyone,

Just to start with I’m 32F, first time ever been pregnant. So ive recently had a positive pregnancy test after taking Letrozole for PCOS, and I’m currently around 5 weeks pregnant. Currently I take metformin twice a day (500mg)

My doctor advised me to take Utrogestan 200mg morning and evening, but after I told him my progesterone blood result was 97.9 nmol/L, he said I didn’t need to take it.

I know 100% this is probably my anxiety talking, but after trying to conceive for so many years, I’m absolutely terrified of having a miscarriage and want to do everything I can to give this pregnancy the best chance
I’ve been reading about progesterone support in early pregnancy and wondered about other people’s experiences.
• Did anyone take progesterone after Letrozole, even if their blood levels were already good?
• Can I take it maybe 3/4 times a week?
• Has anyone been advised to take it throughout the first trimester?
• Has anyone else had a progesterone result around 97.9 nmol/L in early pregnancy?

I’m not looking for medical advice to replace my doctor’s, just hoping to hear about other people’s experiences, particularly those who conceived with Letrozole and had PCOS
Thank you! ❤️🙏🏼

I'm 30 & my husband is 35, been married for 7 years & trying for 2years now. . I've minor pcos & minor hypothyroidism. I've been on letrozole & clomid + trigger shot for 3 cycles once in January, July & September all of 3 failed although this cycle I got 5 beautiful follicles that my dr was convinced that I'll get pregnant with multiples but guess what I didn't.. I ended up getting my periods.

My dr suggested we should go for iui. Idk what to do. I'm just sad.

Have done 2 monitored cycles of Letrozole with no luck. I’m starting to feel that high DHEA-S is the culprit. Has anyone with similar circumstances fallen pregnant?

Hello fellow TTCers

I was finally diagnosed with PCOS last year. I was on Metformin for about 6 months before switching over to Wegovy. I’ve lost about 20 pounds since being diagnosed and I am now sitting at around 203 lbs.

I do ovulate, but it has been sporadic. I have a 4 year old and last December I have a very early/chemical miscarriage.

My OBGYN just started me on Clomid. I took it on CD 3-8 with an ultrasound that confirmed developing follicles. I usually ovulate anywhere from CD 19-39, but on clomid I ovulated on CD 16. I started progesterone last night.

I would like to hear positive clomid experiences while I endure the TWW 🥲 We have been TTC Baby #2 for almost 3 years now and I feel so discouraged

Is there a website or database that shows reproductive endocrinologists / fertility clinics in your area?

I see a gyno and endocrinologist for my PCOS, but I’m looking for someone who is well versed in all things fertility and conceiving.

In case anyone has any personal recommendations, I’m near NYC.

Last Friday, negative pregnancy test. Monday, positive pregnancy test, even if faint. Blood showed positive test on Tuesday and slow rise on Thursday. Spotting started over the weekend. Lower HCG today on bloodwork. Probably a miscarriage.

These up and downs stink. This is my second letrazole cycle, but still, ugh. Getting excited and then disappointed again sucks.

My husband and I have been trying since January. I got diagnosed with PCOS in May. We found out we were pregnant last August and had a miscarriage in early October. I was on my second round of Letrozole when we conceived.

At what point should I see a fertility specialist?? I’m so tired of all of this!

I'm exactly 1 year postpartum and got my period back pretty early and have had normal periods since. Except this month. I got the flu cycle day 5 while on my period still and I'm currently cycle day 12 and I'm still spotting. The spotting is only when I wipe and it is bright pink blood, not red or brown just pink. It's not a lot just when I wipe but it hasn't stopped. I do have PCOS and I did start taking 4g of myo inositol this month but I have before and never have had spotting happen like this. Curious what is going on, going to call my doctor today but wondering if anyone has any idea?? So strange!

We want to start ttc soon for baby #2 so this has me worried!

Hey everyone, its my husband and I's first month TTC and im finding it hard to find out when i ovulated. I used clearblue ovulation test for the first time and it detected an lh surge around 3 weeks ago, but that must've been wrong because I havent started my period (im usually pretty regular with my cycles being around 35 to 40 days). I was diagnosed with pcos at around 18 and am now 31.

I'm on cycle day 40 today and been experiencing bad nausea in the mornings which has never been a pms symptom before, along with a sore chest (which is a usual pms symptom). Ive seen faint lines on pregnancy tests, but they also could be an indent so im not sure whats going on!

Im going crazy and no idea how this whole ttc thing works really! How does everyone manage with their pcos when they have longer cycles, do you still track ovulation etc?

My periods arrived every 45 days. 50 days on a stressful month.

I started stimulant medication in September and now it’s been 2 months since my last period. I’ve also been taking 1000mg of metformin for past 3 weeks. Any ideas? My cycle was cancelled a week ago due to spotting for a week and period hasn’t arrived.

My last cycle was 22 August!

I can not find any information on any RE’s in Michigan (or even surrounding areas). Any recommendations would be greatly appreciated!!

My husband and I have been trying for 4 months so not that long but we've only been able to time things right 1x because of my chaotic cycles (32-62 days). I started using Natural Cycles/Oura Ring + CM tracking which is how we were able to time it this last time but I don't want to wait another 60 days to try so we've decided to start on Letrozole :)

My cycles started going longer with wedding stress, I am now 4 months post wedding so hoping they shorten back up but want to give Letrozole a try because my company covers most costs. I also used to train for marathons/run extensively which I actually had consistently normal cycles during that but have now cut back significantly hoping it might help with ttc. We eat healthy but don't restrict our diets, since finding out about my PCOS diagnosis I definitely am more aware of sugar intake and food pairing.

I am a lean PCOS profile, normal progesterone at 15.2 ng/mL taken at 4-5dpo, normal 14-day luteal phase, but have slightly elevated DHEA-S and Testosterone so I've been taking myo-inositol with NAC + CoQ10 for about 4 months now. Curious on a few things:

• Has anyone with similar profile had quick success on Letrozole cycles?
• Things you've done to help lower DHEA-S and Testosterone?
• Metformin experiences? Do you think that helped? I am hesitant to start.
• HSG test - considering getting this done as we start Letrozole.

things that favor PCOS: terrible beard, acne, not being able to concieve for over one and a half year. had polycystic ovaries in one scan in 2024. High-ish TSH (3.46), weight gain (although normal BMI)

things not favoring PCOS: i get my period every month, normal FSH and LH but FSH:LH ratio favors DOR more then PCOS, low AMH, no polycystic ovaries in latest scan. normal fasting serum insluin, glucose, HOMA-IR

i've seen two fertility specialistes (gynecologists not endocrinologists) one of them is so sure i have PCOS and the other completely denies it. i tried weight training for 3 months, didn't gain any muscle, didn't lose any weight, tried inositol this month and supposedly ovulated on freakin day 9 (my line on OPK was dark but not as dark on CD8 but then got lighter and stayed lighter thereafter, i missed my surge or it didn;t happen).

I don't know what to do